WB, ICC/IF, IHC, IHC-P, KDHost:
Hu, Mu, RtApplications:
WB, ICC/IF, PEP-ELISAHost:
Hu, Mu, Rt, BvApplications:
Applications: Enzyme Activity
Sterol O-acyltransferase 1 (SOAT1), also known as ACAT1, catalyzes the formation of intracellular cholesterol esters in various tissues, such as adult human liver, adrenal glands, macrophages, and kidneys. Specifically, ACAT-1 catalyzes the reversible reaction forming acetoacetyl-CoA from two molecules of acetyl-CoA. Additionaly, the ACAT 1 protein may have a role in lipoprotein assembly and dietary cholesterol absorption, and may also act as a ligase.
Mutations in this gene have been associated with 3-ketothiolase deficiency, an inborn defect of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
|Product By Gene ID
- EC 2.3.1
- mitochondrial acetoacetyl-CoA thiolase
- acetyl-CoA acetyltransferase, mitochondrial
- Acetoacetyl-CoA thiolase
- acetoacetyl Coenzyme A thiolase
- acetyl-Coenzyme A acetyltransferase 1
- EC 22.214.171.124
- acetyl-CoA acetyltransferase 1
Bioinformatics Tool for ACAT1
Discover related pathways, diseases and genes to ACAT1. Need help? Read the Bioinformatics Tool Guide
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