ABHD4 Products

Description

Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis ofN-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains fromN-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate forN-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acylchains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine,lysophosphatidylethanolamine and lysophosphatidylserine

Bioinformatics

Entrez	63874 Human
Uniprot	NM_022060 Human NP_071343.2 Human Q8TB40 Human
Product By Gene ID	63874
Alternate Names	ABH4 abhydrolase domain containing 4 abhydrolase domain-containing protein 4 Alpha/beta-hydrolase 4 EC 3.1.1.- FLJ12816 Lyso-N-acylphosphatidylethanolamine lipase

Diseases related to ABHD4

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Neoplasm Metastasis
Malignant Neoplasms
Malignant Neoplasm Of Ovary

Pathways for ABHD4

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Cell Death
Fertilization
Anoikis
Cell Growth
Oocyte Maturation
Embryo Development

Research Areas for ABHD4

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Lipid and Metabolism

PTMs for ABHD4

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Cleavage
Dephosphorylation

Bioinformatics Tool for ABHD4

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