ABCA4 Products

Antibodies
ABCA4 Antibody (3F4)
ABCA4 Antibody (3F4)
NBP1-30032
Species: Hu, Mu, Bv, Xp
Applications: WB, IHC, IHC-Fr
Host: Mouse Monoclonal
ABCA4 Antibody
ABCA4 Antibody
NBP1-28804
Species: Hu
Applications: PEP-ELISA
Host: Goat Polyclonal
ABCA4 Antibody
ABCA4 Antibody
NB100-93468
Species: Hu, Ca
Applications: PEP-ELISA
Host: Goat Polyclonal
Proteins
Recombinant Human ABCA4 Prote ...
Recombinant Human ABCA4 Protein
H00000024-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
ABCA4 RNAi
ABCA4 RNAi
H00000024-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Product By Gene ID 24
Alternate Names
  • EC 3.6.3
  • STGD1
  • RmP
  • RP19
  • retinal-specific ATP-binding cassette transporter
  • CORD3
  • retina-specific ABC transporter
  • RIM protein
  • photoreceptor rim protein
  • RIM ABC transporter
  • ATP-binding transporter, retina-specific
  • ATP-binding cassette sub-family A member 4
  • ATP binding cassette transporter
  • Stargardt disease protein
  • STGD
  • ATP-binding cassette transporter, retinal-specific
  • ABCRRMP
  • FFMFLJ17534
  • ARMD2DKFZp781N1972
  • ABC10
  • ATP-binding cassette, sub-family A (ABC1), member 4

Research Areas for ABCA4

Find related products by research area and learn more about each of the different research areas below.

ABC Transporters
Lipid and Metabolism
Vision

PTMs for ABCA4

Learn more about PTMs related to ABCA4.

Glycosylation
Phosphorylation
Oxidation
Dephosphorylation

Bioinformatics Tool for ABCA4

Discover related pathways, diseases and genes to ABCA4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.