5'-Nucleotidase/CD73 Products

Antibodies
5'-Nucleotidase/CD73 Antibody ...
5'-Nucleotidase/CD73 Antibody
NBP1-85740
Species: Hu, Mu, Rt, Po
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
5'-Nucleotidase/CD73 Antibody ...
5'-Nucleotidase/CD73 Antibody (4G4)
NBP1-60135
Species: Hu
Applications: WB, Flow, Func, ICC/IF, IHC, IHC-Fr, IP
Host: Mouse Monoclonal
Lysates
5'-Nucleotidase/CD73 Overexpr ...
5'-Nucleotidase/CD73 Overexpressio...
NBL1-13827
Applications: WB
Proteins
5'-Nucleotidase/CD73 Recombin ...
5'-Nucleotidase/CD73 Recombinant P...
H00004907-P01
Species: Hu
Applications: WB, ELISA, PA
5'-Nucleotidase/CD73 Recombin ...
5'-Nucleotidase/CD73 Recombinant P...
NBP2-51548
Species: Hu
Applications: PAGE
5'-Nucleotidase/CD73 Recombin ...
5'-Nucleotidase/CD73 Recombinant P...
NBP1-85740PEP
Species: Hu
Applications: AC
RNAi
5'-Nucleotidase/CD73 RNAi
5'-Nucleotidase/CD73 RNAi
H00004907-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase; EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.[supplied by OMIM]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 4907
Alternate Names
  • CD73 antigen
  • NTE
  • Ecto-5'-nucleotidase
  • 5'-NT
  • Purine 5-Prime-Nucleotidase
  • eNT
  • ecto-5'-nucleotidase
  • eN
  • NT
  • CD73
  • E5NT
  • 5' nucleotidase (CD73)
  • NT55'-nucleotidase
  • EC 3.1.3.5
  • 5'-nucleotidase, ecto (CD73)

Research Areas for 5'-Nucleotidase/CD73

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

PTMs for 5'-Nucleotidase/CD73

Learn more about PTMs related to 5'-Nucleotidase/CD73.

Methylation
Demethylation
Dephosphorylation
Gpi Anchoring
Myristoylation

Bioinformatics Tool for 5'-Nucleotidase/CD73

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Related 5'-Nucleotidase/CD73 Blog Posts

Check out the latest blog posts on 5'-Nucleotidase/CD73.
CD73 (Cluster of differentiation 73, ecto-5'-nucleotidase)
CD73 is a 70kD glycosyl-phosphatidylinositol (GPI)-anchored cell surface molecule that belongs to the 5'-nucleosidase family. It hydrolyzes extracellular nucleotides into membrane permeable nucleosides and is found as both a membrane-bound and soluble...    Read more.
Read more 5'-Nucleotidase/CD73 related blogs.