Species: Hu, Mu, Rt
Applications: WB
Host: Goat Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
HSD11B1 is encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
3290 |
| Alternate Names |
- 11-beta-hydroxysteroid dehydrogenase 1
- EC 1.1.1
- EC 1.1.1.146
- HDL
- HSD11HSD11B
- HSD11LMGC13539
- hydroxysteroid (11-beta) dehydrogenase 1
- member 1
- SDR26C1
|
Research Areas for 11 beta-HSD1
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism
