CD34 antibodies

CD34 (Cluster of differentiation 34, hematopoietic progenitor cell antigen)

CD34 is a cell-surface glycoprotein type 1 transmembrane protein that belongs to the sialomucin family. CD34 comprises of an intracellular cytoplasmic domain with consensus sites for serine, threonine, tyrosine and active protein kinase C (PKC). Because it is differentially glycosylated within different cell types, it has a range of apparent molecular weight sizes. It is a marker for pluripotent hematopoietic stem or progenitor cells and has been extensively used to isolate and characterize these progenitor cells.

CD34 Serves as an Important Marker in Disease Research

CD34 is a membrane protein that aids cells in cell-cell adhesion. Although little is known about its function, CD34 is an important marker for hematopoietic stem cells (HSCs), muscle satellite cells, and endothelial cells.

CD34 Serves as an Important Marker in Disease Research

CD34 is a cell surface glycoprotein that aids cells in cell-cell adhesion. It is expressed on endothelial cells where it is known to bind L-selectin and may aid in migration of T-cells.