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By Jamshed Arslan, Pharm. D., PhD.
We live in a world where 39% of adults are overweight. Our meals trigger the secretion of various gut-derived metabolic hormones called incretins. Fats and carbohydrates in our diet stimulate the release of an incretin from the duodenum called glucose-dependent insulinotropic polypeptide or gastric inhibitory polypeptide (GIP). GIP acts on its receptor (GIPR) in adipocytes and pancreas to promote fatty acid uptake and insulin...
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By Christina Towers, PhD
Over the last two decades the field of autophagy has exploded! Innovative techniques, comprehensive analysis and disease-relevant models have yielded basic and clinical discoveries of consequence. The Nobel Prize for Physiology or Medicine was awarded to Dr. Yoshinori Ohsumi in 2016, for his ground-breaking work in yeast to identify many of the core autophagy proteins. Since then, the field has only expanded. In just the past year, the field has produced numerous...
