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By Jamshed Arslan Pharm.D.
Interneurons transmit impulses between other neurons, in part, to facilitate the birth of neurons. Cortical interneurons themselves arise from the progenitors in the ventral telencephalon, a brain region that generates basal ganglia. The role of mechanistic target of rapamycin (mTOR) signaling in this process is poorly understood even though mTOR is known to determine brain size. By deleting mTOR in mouse interneuron progenitors and their progeny, Dr. Woo-Yang Kim’s team at the University of Nebraska Medical Center, USA found two homeostatic activities of mTOR in...
