Novus Biologicals announces new CCR2 Antibodies

Novus Biologicals recently introduced two antibodies to C C chemokine receptor type 2 (CCR2).  CCR2 is a regulator of monocyte/macrophage trafficking and is upregulated in response to inflammation. The ligand for CCR2 is monocyte chemoattractant protein (MCP-1), a chemokine produced by endothelial cells, smooth muscle cells, and macrophages. Furthermore, resistance to HIV-1 infection or delayed progression to AIDS may be linked to CCR2 polymorphisms.

Novus' new CCR2 antibodies have been positively validated for use in Flow cytometry, Immunocytochemistry and Western blot analysis, where a band at ~42kDa is seen. The immunogens to which these rabbit polyclonal antibodies are made are synthetic peptides made to the N-terminal portion of the human CCR2 protein (catalog number NBP1-48337) and the mouse CCR2 protein (catalog number NBP1-48338).  NBP1-48337 is human-specific, while NBP1-48338 cross-reacts with both human and mouse.

Novus provides other CCR2 antibodies, peptides, proteins, and RNAi which can be found here. CCR2 -related products are also available from Novus, including: MCP1, CCR5, CCR1 and CXCR4.


For more information on these new CCR2 antibodies or to inquire about product collaborations, please contact the Novus Product Development Team by calling 303-730-1950 or via e-mail at

Release Date: 
Monday, October 18, 2010 - 06:00