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 Hypoxia inside solid tumors has been associated with tumor progression and therapy resistance. The discovery of hypoxia-inducible transcription factors (HIFs) has greatly advanced our understanding of the role of hypoxia in these phenomena. HIF-1 alpha is the master transcriptional factor, which binds to HIF-1 beta upon hypoxia to activate the transcription of... |
 October is Breast Cancer Awareness month. Novus Biologicals offers thousands of products for a wide range of applications in the field of breast cancer research. There are many classifications of breast cancer that affect the prognosis and treatment responses of patients. It is estimated that up to 10% of breast cancer cases are due to inherited genes such as tumor suppressors BRCA1... |
 Aging is defined as a deterioration of functional processes in the human body over time, which leads to heightened risk for death and disease1. When it comes to aging and metabolism, this process is characterized by a resistance in insulin, an alteration of body composition and an overall shift in hormone regulation. Evidence that these metabolic processes contribute to aging has been... |
