 Tumor suppressors are genes that protect cells from cancerous transformations. But, occasionally, these genes mutate and a loss in function leads to cancer. This is in contrast to oncogenes, which cause cancer through a mutation resulting in a gain of function. Tumor suppressor genes are often grouped into three categories: Caretakers,... |
Summary: Spotlight on Apoptosis Detection Methods Apoptosis is an important biological process and its defection has been implicated in an extensive variety of diseases. A number of methods have been developed to detect apoptosis. These methods are based on the changes in the different apoptotic events, including plasma membrane alterations, mitochondrial changes, changes in the cytoplasm, DNA modifications and so on. |
Summary:Â In this newsletter, the antibody targets available for studying different aspects of Alzheimer's disease are highlighted.
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Novus Biologicals has recently added a new M6PR (cation independent) monoclonal antibody (... |
Summary: Transcriptional Regulation of Autophagosome Marker LC3 LC3 (microtubule-associated protein 1 light chain 3) is a ubiquitin-like molecule that is the mammalian homologue of the autophagy-related Atg8 encoded product in yeast. Upon autophagic signal, the cytosolic form of LC3 (LC3-I) is conjugated to... |
