Rad9 Products

Description

This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene.

Bioinformatics

Entrez	5883 Human 19367 Mouse
Uniprot	NP_004575.1 Human
Product By Gene ID	5883
Alternate Names	cell cycle checkpoint control protein RAD9A DNA repair exonuclease rad9 homolog A EC 3.1.11.2 hRAD9 RAD9 (S. pombe) homolog RAD9 homolog A (S. pombe) RAD9

Research Areas for Rad9

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Checkpoint signaling
DNA Repair
Tumor Suppressors