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211-TB) induces cytotoxicity in the the L-929 mouse fibroblast cell line in a dose-dependent manner (orange line), as measured by crystal violet staining. Cytotoxicity elicited by Recombinant Human Lymphotoxin-a/TNF-beta (50 pg/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human Lymphotoxin-a/TNF-beta Monoclonal Antibody (Catalog # MAB211). The ND50 is typically 75-600 ng/mL in the presence of the metabolic inhibitor actinomycin D." class="big_lightbox" target="_blank">
211-TB) induces cytotoxicity in the the L-929 mouse fibroblast cell line in a dose-dependent manner (orange line), as measured by crystal violet staining. Cytotoxicity elicited by Recombinant Human Lymphotoxin-a/TNF-beta (0.25 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human Lymphotoxin-a/TNF-beta Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-211-NA). The ND50 is typically <200 µg/mL in the presence of the metabolic inhibitor actinomycin D (1 µg/mL)." class="big_lightbox" target="_blank">
211-TBB) induces cytotoxicity in the the L-929 mouse fibroblast cell line in a dose-dependent manner (orange line), as measured by Resazurin (Catalog # AR002). Cytotoxicity elicited by Recombinant Human Lymphotoxin-a/TNF-beta (0.25 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human Lymphotoxin-a/TNF-beta Monoclonal Antibody (Catalog # MAB621R). The ND50 is typically 8-48 ng/mL in the presence of the metabolic inhibitor actinomycin D." class="big_lightbox" target="_blank">
Species: Hu Applications: B/N, ELISA(Cap) Host: Mouse Monoclonal
TNF-beta (tumor necrosis factor beta, lymphotoxin alpha, TNFSF1, TNF ligand superfamily member 1) a member of the TNF ligand superfamily and a potent lymphoid factor, is mainly produced by activated T and B lymphocytes and leukocytes. TNF-beta is also produced by fibroblasts, astrocytes, myeloma cells, endothelial cells and epithelial cells. TNF-beta mediates inflammatory and immune responses, has cytotoxic activity on tumor cells and other target cells and shares many of the same bioactivities as TNF alpha, including regulation of cell proliferation, differentiation and apoptosis. TNF-beta is not species-specific and human TNF-beta is active on murine cells with a slightly reduced specific activity.
![Neutralization Lymphotoxin-alpha/TNF-beta Antibody (5802) [Unconjugated]](http://images.novusbio.com/images/antibody/TNF-beta_MAB211_Block_Neutralize_9067.jpg)
![Neutralization Lymphotoxin-alpha/TNF-beta Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/TNF-beta_AF-211-NA_Block_Neutralize_8648.jpg)
![Neutralization Lymphotoxin-alpha/TNF-beta Antibody (5807R) [Unconjugated]](http://images.novusbio.com/images/antibody/Lymphotoxinalpha_MAB621R_Block_Neutralize_21530.jpg)
![Sandwich ELISA Lymphotoxin-alpha/TNF-beta Antibody Pair [HRP]](http://images.novusbio.com/fullsize/Lymphotoxin-alpha-TNF-beta-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79553-img0001.jpg)
![N/A Lymphotoxin-alpha/TNF-beta [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_Lymphotoxinalpha_DY211_ELISA_1767.jpg)
![Immunocytochemistry Lymphotoxin-alpha/TNF-beta Antibody (5802) [Unconjugated]](http://images.novusbio.com/images/antibody/TNF-beta_MAB211_Immunocytochemistry_9848.jpg)
