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Somatostatin acts to regulate numerous physiological processes by binding to and activating specific receptors in target tissues. Activation of these receptors by somatostatin--which is secreted by nerve and endocrine cells--regulates the secretion of insulin, glucagon and growth hormone, neuronal excitability in both the brain and the peripheral nervous system, and cell growth. Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary.
Somatostatin Receptor 2 (SSR2), along with SSR1, is expressed at the highest levels in the stomach and jejunum, as well as in the cerebrum and kidneys.
![Immunocytochemistry Somatostatin R2/SSTR2 Antibody (402038) [Unconjugated]](http://images.novusbio.com/fullsize2/Somatostatin_R2_MAB4224_Immunocytochemistry_6614.jpg)
![Intracellular Staining by Flow Cytometry Somatostatin R2/SSTR2 Antibody (402038) [Unconjugated]](http://images.novusbio.com/fullsize2/Somatostatin_R2_MAB4224_Flow_Cytometry_8440.jpg)
![Immunohistochemistry Somatostatin R2/SSTR2 Antibody (402038) [Unconjugated]](http://images.novusbio.com/fullsize2/Somatostatin_R2_MAB4224_Immunohistochemistry_7020.jpg)
