VSTM5 Antibody (2696A) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: Flow
• Clone: 2696A
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 350

VSTM5 Antibody (2696A) [Alexa Fluor® 350] Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Human embryonic kidney cell HEK293-derived human VSTM5
  Met1-His147
  Accession # NP_001138343
• Specificity: Detects human VSTM5 in direct ELISAs.
• Source: N/A
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Purity Statement: Protein A or G purified from cell culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
• Reconstitution Instructions: Reconstitution default not known

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for VSTM5 Antibody (2696A) [Alexa Fluor® 350]

• C11orf90
• V-set and transmembrane domain containing 5
• V-set and transmembrane domain-containing protein 5
• VSTM5

Background

V-set and transmembrane domain-containing protein 5 (VSTM5) is a cell-adhesion like molecule that belongs to the Ig superfamily.  This molecule is expressed in hippocampal neurons.  It regulates neuronal morphology by promoting dendritic protrusions that develop into dendritic spines.  VSTM5 is a novel factor involved in the modulation of the neuronal membrane and a critical element in normal neuronal circuit formation.  It is one of the target genes responsible for variations in patient responses to treatments for major depressive disorder. Overexpression of VSTM5 in utero delays neuronal migration and induces multiple branches in leading processes during corticogenesis.  Glycosylation at individual N-linked glycosylation sites (Asn43, Asn87, Asn101, and Asn108) not only play essential roles in surface expression of VSTM5 but also in the formation of neuronal dendritic filopodia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • NP_001138343()