VSTM5 Antibody (2696A) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Clone: 2696A
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 647

VSTM5 Antibody (2696A) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects human VSTM5 in direct ELISAs.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for VSTM5 Antibody (2696A) [Alexa Fluor™ Plus 647]

• C11orf90
• V-set and transmembrane domain containing 5
• V-set and transmembrane domain-containing protein 5
• VSTM5

Background

V-set and transmembrane domain-containing protein 5 (VSTM5) is a cell-adhesion like molecule that belongs to the Ig superfamily.  This molecule is expressed in hippocampal neurons.  It regulates neuronal morphology by promoting dendritic protrusions that develop into dendritic spines.  VSTM5 is a novel factor involved in the modulation of the neuronal membrane and a critical element in normal neuronal circuit formation.  It is one of the target genes responsible for variations in patient responses to treatments for major depressive disorder. Overexpression of VSTM5 in utero delays neuronal migration and induces multiple branches in leading processes during corticogenesis.  Glycosylation at individual N-linked glycosylation sites (Asn43, Asn87, Asn101, and Asn108) not only play essential roles in surface expression of VSTM5 but also in the formation of neuronal dendritic filopodia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.