USH1C Antibody

Product Discontinued

USH1C Antibody Summary

• Immunogen: In vivo generated recombinate protein fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: USH1C
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot 1:100-1:2000
• Application Notes: This product is useful in ELISA and Western Blot. Use in Immunohistochemistry-Paraffin reported in multiple pieces of scientific literature. Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID: 30380418).

Reactivity Notes

Zebra Fish

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for USH1C Antibody

• AIE75
• AIE-75
• Antigen NY-CO-38/NY-CO-37
• Autoimmune enteropathy-related antigen AIE-75
• deafness, autosomal recessive 18
• DFNB18
• harmonin
• NY-CO-37
• NY-CO-38
• PDZ-45
• PDZ73
• PDZ-73
• PDZ-73/NY-CO-38
• Protein PDZ-73
• Renal carcinoma antigen NY-REN-3
• ush1cpst
• Usher syndrome 1C (autosomal recessive, severe)
• Usher syndrome type-1C protein

Background

USH1C - Usher syndrome 1C (autosomal recessive, severe)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for USH1C Antibody (20920002)(5)

Publications using 20920002

• Blanco-Sanchez B, Clement A, Fierro J et al. Grxcr1 Promotes Hair Bundle Development by Destabilizing the Physical Interaction between Harmonin and Sans Usher Syndrome Proteins. Cell Rep. 2018-10-30 [PMID: 30380418] (ICC/IF, Zebrafish)
• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Blanco-Sanchez B, Clement A, Fierro J Jr et al. Complexes of Usher proteins preassemble at the endoplasmic reticulum and are required for trafficking and ER homeostasis. The Company of Biologists. 2014-05-07 [PMID: 24626987] (IF/IHC, CoIP, WB, Zebrafish)
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.
• Phillips JB, Blanco-Sanchez B, Lentz JJ et al. Harmonin (Ush1c) is required in zebrafish Muller glial cells for photoreceptor synaptic development and function. The Company of Biologists. 2011-11-01 [PMID: 21757509] (WB, IF/IHC, Zebrafish)

Bioinformatics

• Gene Symbol: USH1C
• Entrez:
  • 10083(Human)
• Uniprot:
  • Q9Y6N9(Human)