TLR12 Antibody

Western Blot: TLR12 Antibody [NBP3-12501] - 1:500 antibody dilution in DiluObuffer. Apparent MW is 109 KDa.

• Reactivity: Hu, Pm, Pm
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

TLR12 Antibody Summary

• Immunogen: Synthetic peptide taken within amino acid region 440-470 from mouse TLR12 protein.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TLR12P
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:20000
  • Western Blot 1:500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for TLR12 Antibody

• Gm1365
• TLR12
• toll-like receptor 12

Background

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLR11 does not respond to known TLR ligands but instead respond specifically to uropathogenic bacteria. TLR11-deficient mice are highly susceptible to infection of the kidneys by uropathogenic bacteria, indicating that TLR11 may play a protective role in preventing infection of internal organs of the urogenital system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TLR12P