TIMBIM 1 Antibody Summary
This protein A purified TIMBIM 1 Antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to the amino terminus of human TIMBIM 1 protein. (Uniprot: Q969X1)
Protein A purified
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- ELISA 1:10000
- Immunohistochemistry 10ug/ml
- Western Blot 1:500-1:2000
Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 35 kDa in size corresponding to TMBIM-1 by western blotting in the appropriate cell lysate or extract. To date this antibody has shown the ability to recognize over-expressed TIMBIM 1 but not endogenous protein.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
A BLAST analysis was used to suggest partial cross-reactivity with TIMBIM 1 from mouse and rat sources based on ~88% homology with the immunizing sequence. Cross-reactivity with TIMBIM 1 from other sources has not been determined
Packaging, Storage & Formulations
Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% Sodium Azide
Protein A purified
This product was protein A purified from monospecific antiserum by immunoaffinity chromatography using protein A coupled to agarose beads
Store vial at -20C prior to opening. Aliquot contents and freeze at -20C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4C as an undiluted liquid. Dilute only prior to immediate use.
Alternate Names for TIMBIM 1 Antibody
- TMBIM 1
- Transmembrane BAX inhibitor motif containing 1
- Transmembrane BAX inhibitor motif containing protein 1
TMBIM1 (Transmembrane BAX inhibitor motifcontaining protein 1) is a member of the 7 TMS (7 transmembrane domains) family of receptors known to mediate the activation of various transcription factors. TMBIM1 is identified as a novel modulator of NF-Kappa B activation. A drosophila homolog of this protein (dNMDA1 with 40% homology to hTMBIM1) is reported to be unregulated during aging and oxidative stress.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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