SSEA-4 Antibody (MC-813-70) [Phycoerythrin]

• Applications: Flow
• Clone: MC-813-70
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Phycoerythrin

SSEA-4 Antibody (MC-813-70) [Phycoerythrin] Summary

• Immunogen: 2120Ep human embryonal carcinoma cell line
• Specificity: Recognizes a carbohydrate epitope of SSEA-4 (1, 2).
• Source: N/A
• Isotype: IgG3
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

SSEA-4 is expressed on the surface of human embryonal carcinoma (EC) cells (the pluripotent stem cells of teratocarcinomas), human embryonic germ cells (EG), and human embryonic stem cells (ES). Expression of SSEA-4 is down-regulated following differentiation of human EC cells. In contrast, the differentiation of murine EC and ES cells may be accompanied by an increase in SSEA-4 expression (1-4).

1. Shevinsky, L.H. et al. (1982) Cell 30:697.
2. Kannagi, R. et al. (1983) EMBO J. 2:2355.
3. Thomson, J.A. and J.S. Odorico (2000) Trends Biotechnol. 18:53.
4. Draper, J.S. et al. (2002) J. Anat. 200:249.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.