SMAGP Antibody [Unconjugated]

• Reactivity: Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

SMAGP Antibody [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant rat SMAGP
  Met1-Thr34, Phe56-Ile97
  Accession # Q7TPF1
• Specificity: Detects rat SMAGP in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 40% cross-reactivity with recombinant human SMAGP is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SMAGP
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5-15 ug/mL
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SMAGP Antibody [Unconjugated]

• hSMAGP
• LOC57228
• MGC149453
• MGC149454
• SMAGP
• small cell adhesion glycoprotein
• small cell transmembrane and glycosylated protein
• Small transmembrane and glycosylated protein
• small trans-membrane and glycosylated protein

Background

SMAGP (small transmembrane and glycosylated protein) is a 25 kDa, type III transmembrane glycoprotein that participates in epithelial cell polarity. Rat SMAGP is 97 amino acids (aa) in length and contains no signal sequence. The N-terminal 34 amino acids constitute the extracellular domain and show O-linked glycosylation. The C‑terminal 42 amino acids (56‑97) make up the cytoplasmic region. SMAGP is likely involved in cell adhesion and communication. Relocation of SMAGP from the membrane to the cytosol is associated with tissue disorganization and metastatic transformation. Over the extracellular and cytoplasmic domains, rat SMAGP shares 96% and 66% aa sequence identity with mouse and human SMAGP, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SMAGP
• Uniprot:
  • Q7TPF1()