Respiratory Syncytial Virus Nucleoprotein Antibody (RSV3132 (B023)) [Allophycocyanin]

• Reactivity: V
• Applications: ELISA, ICC/IF, IHC
• Clone: RSV3132 (B023)
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

Respiratory Syncytial Virus Nucleoprotein Antibody (RSV3132 (B023)) [Allophycocyanin] Summary

• Immunogen: Bovine RSV strains: 127, SNK and 9007. Human RSV strains: A/2, Long, Randall and 8/60
• Specificity: Recognizes an epitope within the 42kD RSV nucleoprotein.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 31381610).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Background

Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Respiratory Syncytial Virus Nucleoprotein Antibody (NB100-64752APC)(1)

Publication using NB100-64752APC

• Lingemann M, McCarty T, Liu X et al. The alpha-1 subunit of the Na+,K+-ATPase (ATP1A1) is required for macropinocytic entry of respiratory syncytial virus (RSV) in human respiratory epithelial cells PLoS Pathog. 2019-08-01 [PMID: 31381610] (ICC/IF, Human)