Respiratory Syncytial Virus Nucleoprotein Antibody (RSV3132 (B023)) - BSA Free

• Reactivity: V
• Applications: ELISA, IHC
• Clone: RSV3132 (B023)
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Respiratory Syncytial Virus Nucleoprotein Antibody (RSV3132 (B023)) - BSA Free Summary

• Description: Novus Biologicals Mouse Respiratory Syncytial Virus Nucleoprotein Antibody (RSV3132 (B023)) - BSA Free (NB100-64752) is a monoclonal antibody validated for use in IHC, ELISA and ICC/IF. Anti-Respiratory Syncytial Virus Nucleoprotein Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Bovine RSV strains: 127, SNK and 9007. Human RSV strains: A/2, Long, Randall and 8/60
• Specificity: Recognizes an epitope within the 42kD RSV nucleoprotein.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:100
• Application Notes: Suitable for use as detection reagent with NB100-64495 as capture reagent in sandwich ELISA.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: <0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A purified

Background

Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Respiratory Syncytial Virus Nucleoprotein Antibody (NB100-64752)(2)

Publications using NB100-64752

• Levy M, Chen JW, Kaiser JA et al. Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters. PLoS pathogens 2024-05-23 [PMID: 38739647]
• Lingemann M, McCarty T, Liu X et al. The alpha-1 subunit of the Na+,K+-ATPase (ATP1A1) is required for macropinocytic entry of respiratory syncytial virus (RSV) in human respiratory epithelial cells PLoS Pathog. 2019-08-01 [PMID: 31381610] (Immunocytochemistry/ Immunofluorescence, Virus)