Plasma Cell Marker Antibody (SPM310) [Biotin]

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Product Details

Summary
Reactivity Hu, Rt(-)Species Glossary
Applications IHC, IHC-P
Clone
SPM310
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

Plasma Cell Marker Antibody (SPM310) [Biotin] Summary

Immunogen
Pancreatic cancer-related mucin
Localization
Cytoplasmic
Specificity
It recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this MAb is not suitable for staining frozen tissues.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34407AF350
Alexa Fluor 405 NBP2-34407AF405
Alexa Fluor 488 NBP2-34407AF488
Alexa Fluor 532 NBP2-34407AF532
Alexa Fluor 594 NBP2-34407AF594
Alexa Fluor 647 NBP2-34407AF647
Alexa Fluor 700 NBP2-34407AF700
Alexa Fluor 750 NBP2-34407AF750
Biotin NBP2-34407B
DyLight 350 NBP2-34407UV
DyLight 405 NBP2-34407V
DyLight 488 NBP2-34407G
DyLight 550 NBP2-34407R
DyLight 594 NBP2-34407DL594
DyLight 650 NBP2-34407C
DyLight 680 NBP2-34407FR
DyLight 755 NBP2-34407IR
FITC NBP2-34407F
HRP NBP2-34407H
Janelia Fluor 549 NBP2-34407JF549
Janelia Fluor 646 NBP2-34407JF646

Additional Plasma Cell Marker Products

Array NBP2-34407B

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