NLRP13 Antibody [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 450 SE

NLRP13 Antibody [mFluor Violet 450 SE] Summary

• Immunogen: Antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NALP13. The immunogen is located within amino acids 150 - 200 of NALP13. Amino Acid Squence: QDPNQEEPEMLEEADHRR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NLRP13
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for NLRP13 Antibody [mFluor Violet 450 SE]

• CLR19.7
• leucine rich repeat and pyrin domain containing 13
• NACHT, leucine rich repeat and PYD containing 13
• NACHT, LRR and PYD containing protein 13
• NACHT, LRR and PYD domains-containing protein 13
• NALP13
• NLR family, pyrin domain containing 13
• NOD14
• nucleotide-binding oligomerization domain protein 14
• PAN13

Background

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NLRP13