Ly-49l Antibody (YLI-90) [Biotin]

• Reactivity: Mu
• Applications: Flow
• Clone: YLI-90
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Biotin

Ly-49l Antibody (YLI-90) [Biotin] Summary

• Immunogen: CHO-K1 cells transfected with B6 allele of Ly49I gene
• Specificity: B6 allele of the Ly49I receptor
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Protect conjugated forms from light.

Alternate Names for Ly-49l Antibody (YLI-90) [Biotin]

• Killer cell lectin like receptor subfamily A member 9
• Klra9
• Ly49I receptor
• LY49I1

Background

The monoclonal antibody YLI-90 reacts with the B6 allele of Ly49I, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. (1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. (2) These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The YLI-90 antibody stains approx. 45% of NK1.1+CD3- splenocytes from C57BL/6 mice. (1)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.