LANA2 Antibody (CM-A807) [DyLight 405]


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Product Details

Reactivity Hu, Mu, ViSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Please see the vial label for concentration. If unlisted please contact technical services.

LANA2 Antibody (CM-A807) [DyLight 405] Summary

Recombinant LANA2 fusion protein.
This is specific for KSHV LANA2 (residues 143-310 epitope recognition).
IgG1 Kappa
Protein G purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 405
DyLight 405 (A=400, E=420)
50mM Sodium Borate
0.05% Sodium Azide
Protein G purified


  • Western Blot 2-4 ug/ml
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
Application Notes
This LANA2 (CM-A807) antibody is useful for ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry on frozen and paraffin-embedded sections, Immunoprecipitation and Western Blot. By Western Blot, this antibody recognizes a viral protein in KSHV infected B-cells (~66-70 kDa).

Reactivity Notes

Reacts with viral LANA2 protein and shows no cross-reactivity to cellular proteins. Also reacts with human and mouse viral KSHV proteins.

Alternate Names for LANA2 Antibody (CM-A807) [DyLight 405]

  • LANA 2
  • LANA-2
  • Latency-associated nuclear antigen 2
  • vIRF 3
  • vIRF3
  • vIRF-3


LANA2 (latency-associated nuclear antigen 2; also known as viral interferon regulatory factor 3) is a Kaposi's sarcoma-associated herpesvirus (KSHV) latent protein which is encoded by ORFK10.5 and is exclusively expressed by virus infected B- cells. LANA2 has been shown to be critical in KSHV-mediated tumorigenesis as it inhibits p53 function, dsRNA-activated protein kinase R (PKR)-dependent apoptosis, nuclear factor kB activity, interferon regulatory factor 7-mediated interferon signal transduction and virus-mediated transcriptional activation of the alpha-interferon promoter. LANA2 stabilizes and triggers the induction of HIF-1alpha's transcriptional activity and disrupts PODs (PML oncogenic domains). Moreover, LANA2 has been shown to be required for the survival of primary effusion lymphoma (PEL) cells infected with KSHV alone or dually infected by Epstein-Barr virus (EBV) and KSHV, wherein it shows nuclear and cytoplasmic expression.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for LANA2 Antibody (NB200-167V) (0)

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Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB200-167APC
Biotin Labeled NB200-167B
DyLight 350 Labeled NB200-167UV
DyLight 405LS Labeled NB200-167V3
DyLight 488 Labeled NB200-167G
DyLight 550 Labeled NB200-167R
DyLight 650 Labeled NB200-167C
DyLight 680 Labeled NB200-167FR
DyLight 755 Labeled NB200-167IR
FITC Labeled NB200-167F
HRP Labeled NB200-167H
PE Labeled NB200-167PE
PerCP Labeled NB200-167PCP

Additional LANA2 Antibody (CM-A807) [DyLight 405] Products

LANA2 NB200-167V

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