Lambda Light Chain Antibody (K22-Y)

Immunohistochemistry-Paraffin: Human lambda light chain Antibody (K22-Y) [NBP1-30142] - Formalin fixed, paraffin embedded human tissues (4 um sections) stained with anti - Human Lambda light chain (DB 039) monospecific clonal antibody.

Immunohistochemistry-Paraffin: Human lambda light chain Antibody (K22-Y) [NBP1-30142] - Human lambda light chain Antibody (K22-Y) human tonsil tissue stained with anti-Human Lambda Light Chain antibody.

Immunohistochemistry-Paraffin: Human lambda light chain Antibody (K22-Y) [NBP1-30142] - Formalin fixed, paraffin embedded human tissues (4 um sections) stained with anti - Human Lambda light chain (DB 039) monospecific clonal antibody.

• Reactivity: Hu
• Applications: IHC
• Clone: K22-Y
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

Lambda Light Chain Antibody (K22-Y) Summary

• Description: This antibody is immunoaffinity purified with immunogenic peptide as a ligand.
• Immunogen: Peptide derived from N-terminal sequence of human lambda light chain IgG. Antibody recognizes the epitope between Ala50 - Ser68.
• Specificity: This antibody is specific for the N terminus of the lambda light chain.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: IGLC1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100-1:500
• Application Notes: For use in Immunohistochemistry frozen and paraffin embedded sections. For 0.1ml, 0.5ml and 1.0ml sizes, use recommended dilutions. For 7.0ml and 15.0ml sizes, products should be used undiluted.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Tris/HCl (pH 8.0) and 20 mg/ml BSA
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

Alternate Names for Lambda Light Chain Antibody (K22-Y)

• IGLC
• immunoglobulin lambda constant group

Background

All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain are present in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for Human lambda light chain Antibody (NBP1-30142). (Showing 1 - 1 of 1 FAQ).

1. Hello, is this antibody from clone T15-E? I think there are some different information on the data sheet.
   • Unfortunately product NBP1-30143 has been discontinued, however you may find NBP1-30142 as an alternative to this product.

Bioinformatics

• Gene Symbol: IGLC1
• Uniprot:
  • P01842(Human)