HPx1 Antibody (HIC0-3B3) [DyLight 488]

• Reactivity: Hu
• Applications: Flow, ICC/IF, IHC
• Clone: HIC0-3B3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 488

HPx1 Antibody (HIC0-3B3) [DyLight 488] Summary

• Description: This product is provided as conjugated tissue culture supernatant. Due to the crude preparation of the antibody material, excess dye may remain in the final product. We highly recommend taking necessary precautions, such as adding additional wash steps and running proper controls.
• Immunogen: Human pancreatic enriched exocrine cells
• Localization: Cell surface
• Marker: Exocrine cell Marker
• Specificity: Specific for exocrine cell types.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Tissue culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Tissue culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for HPx1 Antibody (HIC0-3B3) [DyLight 488]

• human pancreatic exocrine cell

Background

Stem cells offer a therapeutic promise for many diseases. In the case of diabetes, stem cells offer the promise that beta cells may be generated ex vivo for the possible transplantation and cure of Type I diabetes (Couri CE, et al.). For this to happen, stem cells will need to be isolated and expanded, they will need to be differentiated toward the beta cell lineage, and the differentiated cell progeny used for transplantation may need to be isolated from complex cell mixtures following differentiation. Appropriate markers targeting cell surface molecules on developing and mature pancreatic cells will be required for such research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HPx1 Antibody (NBP1-18951G)(4)

Publications using NBP1-18951G

• Wang L, Baek S, Prasad G et al. Predictive prioritization of enhancers associated with pancreatic disease risk. Cell genomics 2025-10-16 [PMID: 41106391]
• Ma H, Jeppesen JF, Jaenisch R. Et al. Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive b Cell Destruction Cell Rep Med 2020-11-18 [PMID: 33205073]
  
  Details:
  Citation using the DyLight 488 version of this antibody.
• Arda H, Tsai J, Rosli Y et al A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas Cell Syst 2018-08-27 [PMID: 30145115] (FLOW, FLOW, Human)
  
  Details:
  Citation using the DyLight 488 version of this antibody.
• Enge M, Arda HE, Mignardi M et al. Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns. Autophagy. 2017-05-04 [PMID: 28965763] (FLOW, Human)
  
  Details:
  Citation used the DyLight 650 format of this antibody.