HPx1 Antibody (HIC0-3B3)

Images

 
Immunocytochemistry/ Immunofluorescence: HPx1 Antibody (HIC0-3B3) [NBP1-18951] - Immunofluorescence on frozen section of human pancreas.
Flow Cytometry: HPx1 Antibody (HIC0-3B3) [NBP1-18951] - Analysis of enzyme dispersed human pancreas cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-Fr
Clone
HIC0-3B3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

HPx1 Antibody (HIC0-3B3) Summary

Immunogen
Human pancreatic enriched exocrine cells
Localization
Cell surface
Marker
Exocrine cell Marker
Specificity
Specific for exocrine cell types.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:50-1:100
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Frozen 1:100
Application Notes
This HPx1 (HIC0-3B3) antibody is useful for Immunohistochemistry on acetone fixed frozen sections, Immunocytochemistry/Immunofluorescence and Flow cytometry.
Publications
Read Publications using
NBP1-18951 in the following applications:

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tissue culture supernatant
Preservative
0.05% Sodium Azide
Purity
Tissue culture supernatant

Notes

The estimated concentration for this antibody is 1.0 mg/ml.

Alternate Names for HPx1 Antibody (HIC0-3B3)

  • human pancreatic exocrine cell

Background

Stem cells offer a therapeutic promise for many diseases. In the case of diabetes, stem cells offer the promise that beta cells may be generated ex vivo for the possible transplantation and cure of Type I diabetes (Couri CE, et al.). For this to happen, stem cells will need to be isolated and expanded, they will need to be differentiated toward the beta cell lineage, and the differentiated cell progeny used for transplantation may need to be isolated from complex cell mixtures following differentiation. Appropriate markers targeting cell surface molecules on developing and mature pancreatic cells will be required for such research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HPx1 Antibody (NBP1-18951)(10)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 4 applications: FLOW, Flow, IHC-Fr, WB.


Filter By Application
FLOW
(3)
Flow
(2)
IHC-Fr
(1)
WB
(1)
All Applications
Filter By Species
Human
(8)
All Species
Showing Publications 1 - 10 of 10.
Publications using NBP1-18951 Applications Species
Camunas-Soler, J, Dai, X Q Et al. Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes. Cell Metab May 5 2020 [PMID: 32302527] (WB, Human) WB Human
Arda H, Tsai J, Rosli Y et al A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas Cell Syst Aug 27 2018 [PMID: 30145115] (Flow, Human)

Details:
Citation using the DyLight 488 version of this antibody.
Flow Human
Jakel C, Bergmann F, Toth R et al. Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability Nat Commun. 2017 Nov 06 [PMID: 29109526] (Human) Human
Enge M, Arda HE, Mignardi M et al. Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns. Cell. 2017 Oct 05 [PMID: 28965763] (Human) Human
Cogger KF, Sinha A, Sarangi F et al. Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors Nat Commun 2017 Aug 24 [PMID: 28835709] (Flow, Human) Flow Human
Arda HE, Li L, Tsai J, et al. Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human beta Cell Function. Cell Press. 2016 May 10 [PMID: 27133132] (FLOW, Human) FLOW Human
Nostro MC, Sarangi F, Ogawa S et al. Pancreatic differentiation 2008 [PMID: 23658992]
Dorrell C, Schug J, Lin C et al. Transcriptomes of the major human pancreatic cell types. Diabetologia. 2011 [PMID: 21882062]
Nostro MC, Sarangi F, Ogawa S, Holtzinger A, Corneo B, Li X, Micallef SJ, Park IH, Basford C, Wheeler MB, Daley GQ, Elefanty AG, Stanley EG, Keller G. Stage-specific signaling through TGFbeta family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells. Development;138(5):861-71. 2011 Mar. [PMID: 21270052] (FLOW, Human) FLOW Human
Dorrell, C, et al. Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers. Stem Cell Res;1(3):183-94. 2008 Sep. [PMID: 19383399] (IHC-Fr, FLOW, Human) IHC-Fr, FLOW Human

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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