HPV16 E1+E4 Antibody (HPV16 E1/E4) [HRP]

• Reactivity: V-Vi
• Applications: IHC
• Clone: HPV16 E1/E4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: HRP

HPV16 E1+E4 Antibody (HPV16 E1/E4) [HRP] Summary

• Immunogen: Recombinant human HPV16 E1+E4 fragment (aa 36-41).
• Localization: Nuclear
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Type 16 of Human Papilloma Virus (HPV-16).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Alternate Names for HPV16 E1+E4 Antibody (HPV16 E1/E4) [HRP]

• ATP dependent helicase E1
• E1
• E4
• HPV 16 ATP dependent helicase E1
• HPV 16 E1
• HPV 16 E4
• HPV 16 replication protein E1
• HPV16 ATP dependent helicase E1
• HPV16 E1
• HPV16 E4
• HPV16 replication protein E1
• Human papilloma virus type 16 ATP dependent helicase E1
• Human papilloma virus type 16 E1
• Human papilloma virus type 16 E4
• Human papilloma virus type 16 replication protein E1
• Human papilloma virus type 16
• Human papillomavirus type 16 ATP dependent helicase E1
• Human papillomavirus type 16 E1
• Human papillomavirus type 16 E4
• Human papillomavirus type 16 replication protein E1
• Human papillomavirus type 16
• Replication protein E1
• Replication protein

Background

HPV16 is an ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins. HPV16, in comparison to HPV types 6 and 11, is more often associated with malignant genital cancers in humans. This antibody is of value in monitoring the progress of HPV infection from benign lesions to invasive cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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