HPV16 E1+E4 Antibody (HPV16 E1/E4) [Alexa Fluor® 532]

• Reactivity: V-Vi
• Applications: IHC
• Clone: HPV16 E1/E4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

HPV16 E1+E4 Antibody (HPV16 E1/E4) [Alexa Fluor® 532] Summary

• Immunogen: Recombinant human HPV16 E1+E4 fragment (aa 36-41).
• Localization: Nuclear
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Type 16 of Human Papilloma Virus (HPV-16).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for HPV16 E1+E4 Antibody (HPV16 E1/E4) [Alexa Fluor® 532]

• ATP dependent helicase E1
• E1
• E4
• HPV 16 ATP dependent helicase E1
• HPV 16 E1
• HPV 16 E4
• HPV 16 replication protein E1
• HPV16 ATP dependent helicase E1
• HPV16 E1
• HPV16 E4
• HPV16 replication protein E1
• Human papilloma virus type 16 ATP dependent helicase E1
• Human papilloma virus type 16 E1
• Human papilloma virus type 16 E4
• Human papilloma virus type 16 replication protein E1
• Human papilloma virus type 16
• Human papillomavirus type 16 ATP dependent helicase E1
• Human papillomavirus type 16 E1
• Human papillomavirus type 16 E4
• Human papillomavirus type 16 replication protein E1
• Human papillomavirus type 16
• Replication protein E1
• Replication protein

Background

HPV16 is an ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins. HPV16, in comparison to HPV types 6 and 11, is more often associated with malignant genital cancers in humans. This antibody is of value in monitoring the progress of HPV infection from benign lesions to invasive cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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