Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody - BSA Free

Staining of human cell line Hep-G2 shows localization to nucleoplasm.

• Reactivity: Hu, Mu, Rt
• Applications: ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody - BSA Free Summary

• Immunogen: This antibody has been engineered to specifically recognize the recombinant protein Heterogeneous Nuclear Ribonucleoprotein (A1-like) using the following amino acid sequence: GNFGGRSSGPYGGGGQYFAKPQNQGG
• Predicted Species: Mouse (96%), Rat (96%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HNRNPA1L2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 µg/ml
• Application Notes: For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody - BSA Free

• heterogeneous nuclear ribonucleoprotein A1-like 2
• hnRNP A1-like 2
• hnRNP core protein A1-like 2
• HNRNPA1L
• LOC144983
• MGC102957

Background

The HNRNPA1 gene encodes a heterogeneous nuclear ribonucleoprotein A1-like (part of the hnRNPs) that functions in various processes such as the ordering of pre-mRNA into hnRNP particles, the transport of poly(A) mRNA to the cytoplams from the nucleus, as well as plays a part in the regulation of splice site selection. Additionally, HNRNPA1 also functions in HCV RNA replication. This gene functions in mRNA splicing and processing, coregulation of adrogen receptor activity, and in translational control. it has been known to interact with various genes such as DDV5, ILF3, DDX17, HNRNPC, and ABHD16A. HNRNPA1 has been researched in various diseases including: cystic fibrosis, colorectal cancer, crohn's disease, spinal cord disease, human t-cell leukemia virus type 1 and type 2, muscular atrophy, stomatitis, and metastasis efficiency.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HNRNPA1L2