Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody (SR2418)

Western Blot: Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody (SR2418) [NBP3-27719] - Western blot analysis of Heterogeneous Nuclear Ribonucleoprotein (A1-like) in K562, C6, 3T3, Hela lysates

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: SR2418
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody (SR2418) Summary

• Description: Novus Biologicals Rabbit Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody (SR2418) (NBP3-27719) is a recombinant monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthetic peptide of human Heterogeneous Nuclear Ribonucleoprotein (A1-like) (Uniprot #: Q32P51)
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: HNRNPA1L2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-1:100
  • Western Blot 1:500-1:1000
• Theoretical MW: 34 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Purity: Affinity purified

Alternate Names for Heterogeneous Nuclear Ribonucleoprotein (A1-like) Antibody (SR2418)

• heterogeneous nuclear ribonucleoprotein A1-like 2
• hnRNP A1-like 2
• hnRNP core protein A1-like 2
• HNRNPA1L
• LOC144983
• MGC102957

Background

The HNRNPA1 gene encodes a heterogeneous nuclear ribonucleoprotein A1-like (part of the hnRNPs) that functions in various processes such as the ordering of pre-mRNA into hnRNP particles, the transport of poly(A) mRNA to the cytoplams from the nucleus, as well as plays a part in the regulation of splice site selection. Additionally, HNRNPA1 also functions in HCV RNA replication. This gene functions in mRNA splicing and processing, coregulation of adrogen receptor activity, and in translational control. it has been known to interact with various genes such as DDV5, ILF3, DDX17, HNRNPC, and ABHD16A. HNRNPA1 has been researched in various diseases including: cystic fibrosis, colorectal cancer, crohn's disease, spinal cord disease, human t-cell leukemia virus type 1 and type 2, muscular atrophy, stomatitis, and metastasis efficiency.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HNRNPA1L2