Feline Leukaemia Virus gp70 Antibody (C11D8)

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Product Details

Summary
Reactivity ViSpecies Glossary
Applications WB, Flow, IHC, IHC-Fr, IHC-P, IP
Clone
C11D8
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Feline Leukaemia Virus gp70 Antibody (C11D8) Summary

Immunogen
Made to Viral FELINE LEUKAEMIA VIRUS gp70
Specificity
NB100-65565 recognizes the gp85/gp70 envelope glycoprotein of feline leukaemia virus. The antibody specifically recognizes the epitope defined by amino acids 214-218 of the gp70 sequence (aa MGPNL). Some weak cross-reactivity with the sequence MGPLL found in the FeLV p15e membrane protein may also occur. This antibody effectively neutralises all three FeLV subgroups (A,B and C).
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Flow Cytometry 1:10-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
Application Notes
Removal of sodium azide is recommended prior to use in functional assays.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for Feline Leukaemia Virus gp70 Antibody (C11D8)

  • Env polyprotein
  • Feline Leukemia Virus glycoprotein 70
  • Glycoprotein gp70 [Precursor]
  • GP70 envelope protein
  • gp70 protein (SU)
  • p15E protein (TM)
  • p15E protein

Background

FeLV is a retrovirus (family Oncovirinae) that can cause severe immunosuppression, severe non regenerative anemia, and a variety of neoplasms. The 3 main subtypes (FeLVA, FeLVB and FeLVC) may act independently or together to cause a variety of diseases. The major envelope glycoprotein (gp70) is used to bind to target cells and varies with the FeLV subtype.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Feline Leukaemia Virus gp70 Antibody (NB100-65565) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NB100-65565AF405
Alexa Fluor 488 Labeled NB100-65565AF488
Alexa Fluor 647 Labeled NB100-65565AF647
Alexa Fluor 700 Labeled NB100-65565AF700
Allophycocyanin Labeled NB100-65565APC
DyLight 350 Labeled NB100-65565UV
DyLight 405 Labeled NB100-65565V
DyLight 488 Labeled NB100-65565G
DyLight 680 Labeled NB100-65565FR
DyLight 755 Labeled NB100-65565IR
PE Labeled NB100-65565PE
PerCP Labeled NB100-65565PCP

Additional Feline Leukaemia Virus gp70 Products

Feline Leukaemia Virus gp70 NB100-65565

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