Feline Leukaemia Virus gp70 Antibody (C11D8) [Alexa Fluor® 700]

• Reactivity: V-Vi
• Applications: WB, Flow, IHC, IP
• Clone: C11D8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 700

Feline Leukaemia Virus gp70 Antibody (C11D8) [Alexa Fluor® 700] Summary

• Immunogen: Made to Viral FELINE LEUKAEMIA VIRUS gp70
• Specificity: NB100-65565 recognizes the gp85/gp70 envelope glycoprotein of feline leukaemia virus. The antibody specifically recognizes the epitope defined by amino acids 214-218 of the gp70 sequence (aa MGPNL). Some weak cross-reactivity with the sequence MGPLL found in the FeLV p15e membrane protein may also occur. This antibody effectively neutralises all three FeLV subgroups (A,B and C).
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Feline Leukaemia Virus gp70 Antibody (C11D8) [Alexa Fluor® 700]

• Env polyprotein
• Feline Leukemia Virus glycoprotein 70
• Glycoprotein gp70 [Precursor]
• GP70 envelope protein
• gp70 protein (SU)
• p15E protein (TM)
• p15E protein

Background

FeLV is a retrovirus (family Oncovirinae) that can cause severe immunosuppression, severe non regenerative anemia, and a variety of neoplasms. The 3 main subtypes (FeLVA, FeLVB and FeLVC) may act independently or together to cause a variety of diseases. The major envelope glycoprotein (gp70) is used to bind to target cells and varies with the FeLV subtype.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.