Cortisol Antibody (BGN/C53) - BSA Free

• Reactivity: All-NA
• Applications: ELISA
• Clone: BGN/C53
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Cortisol Antibody (BGN/C53) - BSA Free Summary

• Description: Novus Biologicals Mouse Cortisol Antibody (BGN/C53) - BSA Free (NB100-62484) is a monoclonal antibody validated for use in ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Cortisol-3-BSA
• Specificity: This product recognises the glucocorticoid hormone cortisol, produced in the adrenal cortex and involved in responses to stress. Cross reactivity: Cortisol 100%, Corticosterone 50%, Prednisolone 15%, 11-Desoxycortisol, <0.1% Cortisone,<0.1% 17-a-OH Progesterone, <0.1%.
• Isotype: IgG3
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:500-1:5000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for Cortisol Antibody (BGN/C53) - BSA Free

• Compound F
• Cortisol
• Hydrocortisone

Background

Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.