Cortisol Antibody (BGN/C53) [mFluor Violet 610 SE]

• Reactivity: All-NA
• Applications: ELISA
• Clone: BGN/C53
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

Cortisol Antibody (BGN/C53) [mFluor Violet 610 SE] Summary

• Immunogen: Cortisol-3-BSA
• Specificity: This product recognises the glucocorticoid hormone cortisol, produced in the adrenal cortex and involved in responses to stress. Cross reactivity: Cortisol 100%, Corticosterone 50%, Prednisolone 15%, 11-Desoxycortisol, <0.1% Cortisone,<0.1% 17-a-OH Progesterone, <0.1%.
• Isotype: IgG3
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Cortisol Antibody (BGN/C53) [mFluor Violet 610 SE]

• Compound F
• Cortisol
• Hydrocortisone

Background

Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.