BCR/ABL Antibody (4C12) - BSA Free

• Reactivity: Hu
• Applications: Func, ICC/IF, IHC
• Clone: 4C12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

BCR/ABL Antibody (4C12) - BSA Free Summary

• Immunogen: BCR/ABL peptide
• Localization: Cytoplasmic
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:40 - 1:80
  • Immunohistochemistry 1:10 - 1:500
  • Radioimmunoassay 1:100 - 1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for BCR/ABL Antibody (4C12) - BSA Free

• ABL
• ALL
• BCR ABL fusion protein
• BCR/ABL fusion protein
• bcr/abl
• Bcr/c abl oncogene protein
• BCR-ABL fusion protein
• BCRe18/ABL1e3 fusion protein
• breakpoint cluster region protein
• c-ABL
• CML
• D22S662
• JTK7
• p150
• PHL

Background

The BCR gene is involved in the 9:22 translocation that generates the Philadelphia chromosome both in chronic myeloid leukemia (CML) and in a proportion of cases of acute lymphocytic leukemia (ALL). A 5' bcr sequence becomes fused to an abl sequence (including tyrosine kinase domain sequences) from chromosome 9 and results in the production of a chimaeric BCR-ABL protein with enhanced kinase activity. These antibodies may be useful for studies of the oncogene and have potential diagnostic and prognostic applications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Entrez:
  • 613(Human)
• Uniprot:
  • P11274()