BCR/ABL Antibody (4C12) - BSA Free

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC, RIA
Clone
4C12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

BCR/ABL Antibody (4C12) - BSA Free Summary

Immunogen
BCR-ABL peptide
Localization
Cytoplasmic
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:40 - 1:80
  • Immunohistochemistry 1:10 - 1:500
  • Radioimmunoassay 1:100 - 1:2000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for BCR/ABL Antibody (4C12) - BSA Free

  • ABL
  • ALL
  • BCR ABL fusion protein
  • BCR/ABL fusion protein
  • bcr/abl
  • Bcr/c abl oncogene protein
  • BCR-ABL fusion protein
  • BCRe18/ABL1e3 fusion protein
  • breakpoint cluster region protein
  • c-ABL
  • CML
  • D22S662
  • JTK7
  • p150
  • PHL

Background

The BCR gene is involved in the 9:22 translocation that generates the Philadelphia chromosome both in chronic myeloid leukemia (CML) and in a proportion of cases of acute lymphocytic leukemia (ALL). A 5' bcr sequence becomes fused to an abl sequence (including tyrosine kinase domain sequences) from chromosome 9 and results in the production of a chimaeric BCR-ABL protein with enhanced kinase activity. These antibodies may be useful for studies of the oncogene and have potential diagnostic and prognostic applications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for BCR Antibody (NB100-2665) (0)

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Secondary Antibodies

 

Isotype Controls

Additional BCR/ABL Products

Array NB100-2665

Research Areas for BCR Antibody (NB100-2665)

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Blogs on BCR/ABL

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Contact Information

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Bioinformatics

Entrez
Uniprot