BCR/ABL Antibody (4C12)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC, RIA
Clone
4C12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

BCR/ABL Antibody (4C12) Summary

Immunogen
BCR-ABL peptide
Localization
Cytoplasmic
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:40 - 1:80
  • Immunohistochemistry 1:10 - 1:500
  • Radioimmunoassay 1:100 - 1:2000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for BCR/ABL Antibody (4C12)

  • ABL
  • ALL
  • BCR ABL fusion protein
  • BCR/ABL fusion protein
  • bcr/abl
  • Bcr/c abl oncogene protein
  • BCR-ABL fusion protein
  • BCRe18/ABL1e3 fusion protein
  • breakpoint cluster region protein
  • c-ABL
  • CML
  • D22S662
  • JTK7
  • p150
  • PHL

Background

The BCR gene is involved in the 9:22 translocation that generates the Philadelphia chromosome both in chronic myeloid leukemia (CML) and in a proportion of cases of acute lymphocytic leukemia (ALL). A 5' bcr sequence becomes fused to an abl sequence (including tyrosine kinase domain sequences) from chromosome 9 and results in the production of a chimaeric BCR-ABL protein with enhanced kinase activity. These antibodies may be useful for studies of the oncogene and have potential diagnostic and prognostic applications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for BCR Antibody (NB100-2665) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NB100-2665AF350
Alexa Fluor 405 NB100-2665AF405
Alexa Fluor 488 NB100-2665AF488
Alexa Fluor 532 NB100-2665AF532
Alexa Fluor 594 NB100-2665AF594
Alexa Fluor 647 NB100-2665AF647
Alexa Fluor 700 NB100-2665AF700
Alexa Fluor 750 NB100-2665AF750
Biotin NB100-2665B
DyLight 350 NB100-2665UV
DyLight 405 NB100-2665V
DyLight 488 NB100-2665G
DyLight 550 NB100-2665R
DyLight 594 NB100-2665DL594
DyLight 650 NB100-2665C
DyLight 680 NB100-2665FR
DyLight 755 NB100-2665IR
FITC NB100-2665F
HRP NB100-2665H
Janelia Fluor 549 NB100-2665JF549
Janelia Fluor 646 NB100-2665JF646

Additional BCR/ABL Products

Array NB100-2665

Research Areas for BCR Antibody (NB100-2665)

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Blogs on BCR/ABL

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Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

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Bioinformatics

Entrez
Uniprot