Aspergillus Antibody

• Reactivity: Fu
• Applications: ELISA, IHC, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

Aspergillus Antibody Summary

• Immunogen: Soluble extract from A. fumigatus, A. flavus, A. niger and A. terreus.
• Specificity: Reactive with soluble proteins from common Aspergillus species. Antiserum is not absorbed and may react with related microorganisms.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunofluorescence
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Reactive with soluble proteins from common Aspergillus species. Antiserum is not absorbed and may react with related microorganisms.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 10mM PBS (pH 7.2)
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Aspergillus Antibody

• Aspergillus spp

Background

The genus Aspergillus includes over 185 species. Around 20 species have been reported as causative agents of opportunistic infections in humans. Among these, Aspergillus fumigatus is the most commonly isolated species, followed by Aspergillus flavus. Aspergillus fumigatus is the major cause of aspergillosis. This organism causes both invasive and allergic aspergillosis. Aspergillus also produce fungal toxins called mycotoxins. Aflatoxin is produced by Aspergillus flavus as it grows on corn and peanuts. The toxin is poisonous to humans by ingestion and causes liver disease. Aspergillus nidulans can produce the mycotoxin sterigmatocystin. This toxin has been shown to produce liver and kidney damage in lab animals. Aspergillus oschraceus,found in grains, soil and salted food products can produce a kidney toxin called oschratoxin A, which may produce oschratoxicosis in humans. Ochratoxin may also be produced by other aspergillus and penicillium species. Other toxins that can be produced by this fungus include penicillic acid, xanthomegnin and viomellein. Aspergillus infections have a very high mortality rate. Their incidence is growing because of the increased number of immunocompromised patients. Previous to antibodies such as these, special stains were used to identify aspergillus. Aspergillus oryzae and Aspergillus niger are used extensively in industrial scale fermentation to produce enzymes for processing household food and drink products.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for Aspergillus Antibody (NB600-1374). (Showing 1 - 1 of 1 FAQ).

1. I have couple of questions related to your Aspergillus antibodies # NB600-1374 and NB100-64511: Do you know if they recognize also A. versicolor among the other sub-species? Are these suitable for lateral flow -applications?
   • All of our known cross-reactivity and testing information is listed on the datasheets for these products. It appears that neither has been specifically tested for reactivity to A. versicolor but most likely both will cross-react. These products have only been tested for the applications listed on the datasheets. Both NB100-64511 and NB600-1374 work in IHC/ICC, so it is expected that they will work for lateral flow-applications as well. NB100-64511 works in ICC and this is most similar, so I would recommend this product for your assay.