LHPP Antibodies
We offer LHPP Antibodies for use in common research applications: Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot. Each LHPP Antibody is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. Our LHPP Antibodies can be used in a variety of model species: Bovine, Human, Mouse, Rabbit, Rat. Use the list below to choose the LHPP Antibody which is most appropriate for your research; you can click on each one to view full technical details, images, references, reviews and related products. Choose from our LHPP polyclonal antibodies.
Alternate Names for LHPP Antibodies
anti-LHPP antibody, anti-FLJ44846 antibody, anti-HDHD2B antibody, anti-hLHPP antibody, anti-MGC117251 antibody, anti-MGC142189 antibody, anti-MGC142191 antibody, anti-phospholysine phosphohistidine inorganic pyrophosphate phosphatase antibody
6 Results for "lhpp" in Primary Antibodies
![Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83272] - Staining of human cerebral cortex, gastrointestinal, lymphoid tissues and testis using Anti-NFIA antibody (A) NBP1-83272 shows similar protein distribution across tissues to independent antibody NBP1-83273 (B).](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunohistochemistry-Paraffin-NBP1-83272-img0021.jpg "<b>Independent Antibodies Validation. </b>Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83272] - Staining of human cerebral cortex, gastrointestinal, lymphoid tissues and testis using Anti-NFIA antibody (A) NBP1-83272 shows similar protein distribution across tissues to independent antibody NBP1-83273 (B).")
![<b>Independent Antibodies Validation. </b>Immunocytochemistry/Immunofluorescence: LHPP Antibody [NBP1-83272] - Staining of human cell line U-2 OS shows localization to nuclear speckles & cytosol. Antibody staining is shown in green.](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-83272-img0007.jpg)
![Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83272] - Staining of human cerebral cortex shows moderate positivity in neurons and glial cells.](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunohistochemistry-Paraffin-NBP1-83272-img0017.jpg)
![Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83272] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunohistochemistry-Paraffin-NBP1-83272-img0018.jpg)
![Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83272] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunohistochemistry-Paraffin-NBP1-83272-img0019.jpg)
![Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83272] - Staining of human skeletal muscle shows very weak positivity in myocytes.](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunohistochemistry-Paraffin-NBP1-83272-img0020.jpg)
![Immunohistochemistry: LHPP Antibody - BSA Free [NBP3-46025] - Immunohistochemistry of paraffin-embedded human kidney using (LHPP antibody) at dilution of 1:100](http://images.novusbio.com/fullsize/nbp3-46025_rabbit-lhpp-pab-bsa-free-284202511511050.jpg "Immunohistochemistry: LHPP Antibody - BSA Free [NBP3-46025] - Immunohistochemistry of paraffin-embedded human kidney using (LHPP antibody) at dilution of 1:100")
![Immunocytochemistry/ Immunofluorescence: LHPP Antibody - BSA Free [NBP3-46025] - Immunofluorescent analysis of Hela cells, using LHPP antibody at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red)](http://images.novusbio.com/fullsize/nbp3-46025_rabbit-lhpp-pab-bsa-free-284202511463190.jpg)
![Western Blot: LHPP Antibody - BSA Free [NBP3-46025] - Human brain tissue were subjected to SDS PAGE followed by western blot with (LHPP antibody) at dilution of 1:500](http://images.novusbio.com/fullsize/nbp3-46025_rabbit-lhpp-pab-bsa-free-284202511483457.jpg)
![Western Blot: LHPP Antibody [NBP3-04615] - Analysis of extracts of various cell lines, using LHPP antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit](http://images.novusbio.com/fullsize/LHPP-Antibody-Western-Blot-NBP3-04615-img0002.jpg "Western Blot: LHPP Antibody [NBP3-04615] - Analysis of extracts of various cell lines, using LHPP antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit")
![Immunocytochemistry/Immunofluorescence: LHPP Antibody [NBP3-04615] - Analysis of L929 cells using LHPP antibody at dilution of 1:100. Blue: DAPI for nuclear staining.](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunocytochemistry-Immunofluorescence-NBP3-04615-img0001.jpg)
![Western Blot: LHPP Antibody [NBP1-70600] - A549 cell lysate, concentration 0.2-1 ug/ml.](http://images.novusbio.com/fullsize/LHPP-Antibody-Western-Blot-NBP1-70600-img0002.jpg "Western Blot: LHPP Antibody [NBP1-70600] - A549 cell lysate, concentration 0.2-1 ug/ml.")
![Western Blot: LHPP Antibody [NBP2-87721] - WB Suggested Anti-Lhpp Antibody. Titration: 1.0 ug/ml. Positive Control: Mouse Heart](http://images.novusbio.com/fullsize/LHPP-Antibody-Western-Blot-NBP2-87721-img0001.jpg "Western Blot: LHPP Antibody [NBP2-87721] - WB Suggested Anti-Lhpp Antibody. Titration: 1.0 ug/ml. Positive Control: Mouse Heart")
![Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83273] - Analysis in human cerebral cortex and skeletal muscle tissues. Corresponding LHPP RNA-seq data are presented for the same tissues.](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunohistochemistry-Paraffin-NBP1-83273-img0020.jpg "<b>Orthogonal Strategies Validation. </b>Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83273] - Analysis in human cerebral cortex and skeletal muscle tissues. Corresponding LHPP RNA-seq data are presented for the same tissues.")
![<b>Independent Antibodies Validation and Orthogonal Strategies Validation.</b>Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83273] - Staining of human cerebral cortex, kidney, liver and skeletal muscle using Anti-LHPP antibody (A) NBP1-83273 shows similar protein distribution across tissues to independent antibody NBP1-83272 (B).](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunohistochemistry-Paraffin-NBP1-83273-img0023.jpg)
![<b>Orthogonal Strategies Validation. </b>Western Blot: LHPP Antibody [NBP1-83273] - Analysis in human cell lines A-431 and Caco-2 using anti-LHPP antibody. Corresponding LHPP RNA-seq data are presented for the same cell lines. Loading control: anti-PPIB.](http://images.novusbio.com/fullsize/LHPP-Antibody-Western-Blot-NBP1-83273-img0009.jpg)
![Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83273] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunohistochemistry-Paraffin-NBP1-83273-img0014.jpg)
![Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83273] - Staining of human skeletal muscle shows no positivity in myocytes as expected.](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunohistochemistry-Paraffin-NBP1-83273-img0015.jpg)
![Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83273] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons and glial cells.](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunohistochemistry-Paraffin-NBP1-83273-img0021.jpg)
![Immunohistochemistry-Paraffin: LHPP Antibody [NBP1-83273] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.](http://images.novusbio.com/fullsize/LHPP-Antibody-Immunohistochemistry-Paraffin-NBP1-83273-img0022.jpg)
![Immunohistochemistry: LHPP Antibody [NBP1-83273] - Representative images of lung metastasis and hematoxylin-and-eosin staining. Metastatic nodules were counted with or without a microscope and recorded. Overexpression of LHPP in MGC-803 cells significantly reduced the number of metastatic lesions in the lungs. Scale bars = 200 um. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/35568711/) licensed under a CC-BY license.](http://images.novusbio.com/fullsize/nbp1-83273_rabbit-polyclonal-lhpp-antibody-2552023151490.jpg)
![Immunohistochemistry: LHPP Antibody [NBP1-83273] - METTL14-mediated m6A modification represses LHPP expression in GC.A The potential m6A sites were predicted by SRAMP. B, C qRT-PCR & western blot assays revealed the mRNA & protein expression, respectively, of LHPP in GC cells with knockdown or overexpression of METTL14. D IHC staining of LHPP & METTL14 in TMAs. Scale bars = 200 μm. E m6A immunoprecipitation & qRT-PCR assays showed the relative percentage of LHPP mRNA with methylation. Data were analyzed using the Wilcoxon test. *P < 0.05, **P < 0.01, ***P < 0.001, ns no significant difference, GC gastric cancer, qRT-PCR quantitative reverse transcription-polymerase chain reaction, IHC immunohistochemical, TMS tissue microarrays. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/35568711), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nbp1-83273_rabbit-polyclonal-lhpp-antibody-310202415392589.jpg)
![Immunohistochemistry: LHPP Antibody [NBP1-83273] - LHPP inhibits GC proliferation & metastasis in vitro.A Basic protein expression of LHPP in GC cell lines (MKN-28, AGS, SNU-216, MGC-803, BGC, MKN-45, HGC-27 & KATO III) was detected by western blotting. B HGC-27 cells with stable LHPP overexpression or MGC-803 cells with LHPP knockdown were created. The changes in LHPP expression were confirmed using western blotting. C, D The proliferative ability of stably transfected HGC-27 or MGC-803 cells was investigated via CCK-8 assays & colony formation. CCK-8 data were analyzed using a two-way analysis of variance. Colony number data were analyzed using the Wilcoxon test. Scale bars = 1 cm. E The drug resistance of stably transfected HGC-27 or MGC-803 cells was investigated via IC50 assays & colony formation. F Transwell assays with stably transfected HGC-27 & MGC-803 cells were performed. Representative images & quantification of the results are presented. Scale bars = 100 μm. Cell number data were analyzed using the Wilcoxon test. ***P < 0.001, GC gastric cancer, OXA Oxaliplatin. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/35568711), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nbp1-83273_rabbit-polyclonal-lhpp-antibody-31020241611471.jpg)
![Immunohistochemistry: LHPP Antibody [NBP1-83273] - LHPP suppresses aerobic glycolysis.A Relative mRNA expression levels of glycolytic genes & glutamine transporters in LHPP-overexpressing or LHPP-knockdown MGC-803 cells & control cells by qPCR. B Protein expression levels of glycolytic genes & glutamine transporters in LHPP-overexpressing or LHPP-knockdown MGC-803 cells & control cells on western blot. C IHC staining of LHPP & HIF1A in TMAs & their correlation. Scale bars = 100 μm. D Oxygen consumption rate & extracellular acidification rate of LHPP-overexpressing or LHPP-knockdown MGC-803 cells & control cells were measured using the Seahorse Bioscience XF96 analyser. E Human phosphokinase microarray assay analysis of the conditioned medium from stably transfected HGC-27 cells. A summary of the relative signal intensities of the indicated proteins is shown. G, H IHC staining of LHPP & p-GSK3b in TMAs & their correlation. Scale bars = 200 μm. F Combined LHPP & GSK3b by co-immunoprecipitation. I Protein expression levels of the Wnt pathway in LHPP-overexpressing or LHPP-knockdown MGC-803 cells & control cells on western blot. Data were analyzed using the Wilcoxon test. *P < 0.05, **P < 0.01, ***P < 0.001, KEGG Kyoto encyclopaedia of genes & genomes, GO gene ontology, qPCR quantitative polymerase chain reaction, IHC immunohistochemical, TMA tissue microarray. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/35568711), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nbp1-83273_rabbit-polyclonal-lhpp-antibody-31020241613610.jpg)