Neuregulin-1/NRG1 Products

Description

Position of the Chimera RNAi. The related RNAi products listed were designed from different accesion number but sharing the same RNAi sequence. Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID	3084
Alternate Names	ARIA GGF2 GGFglial growth factor Heregulin-1 HGL HGLneu differentiation factor HRG HRG1 HRG1-alpha HRG1-beta 1 HRGAneuregulin 1 type IV beta 1a MST131 MSTP131 NDFheregulin, alpha (45kD, ERBB2 p185-activator) neuregulin 1 type IV beta 3 neuregulin 1 Neuregulin1 Neuregulin-1 NRG1 pro-neuregulin-1, membrane-bound isoform pro-NRG1 sensory and motor neuron derived factor SMDF

Research Areas for Neuregulin-1/NRG1

Find related products by research area and learn more about each of the different research areas below.

Glia Markers
Growth and Development
Neuronal Cell Markers
Neuroscience
Oligodendrocyte Cell Markers
Signal Transduction