ICEBERG Products

Description

Caspase recruitment domain-containing protein 18, also known as CARD18, is a member of the death-domain-fold superfamily that is induced by proinflammatory stimuli. It consists essentially only of a CARD, inhibits generation of IL-1b by interacting with caspase-1 and preventing association with RIP 2. The association of CARD18 with caspase-1 is facilitated by the charge-charge interactions between the prodomain of caspase-1 and the surface charge of CARD18. Recombinant human CARD18 proetin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Bioinformatics

Product By Gene ID	59082
Alternate Names	caspase recruitment domain family, member 18 Caspase-1 inhibitor Iceberg ICEBERG caspase-1 inhibitor ICEBERGcaspase recruitment domain-containing protein 18 pseudo-ICE UNQ5804

Research Areas for ICEBERG

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer