Home » GRK2 Products

We're moving to rndsystems.com. Come with us!

After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.

Register on R&D Systems

GRK2 Products

Antibodies
GRK2 Antibody (3F8)
GRK2 Antibody (3F8)
NBP2-37611
Immunohistochemistry GRK2 Antibody (3F8)
Western Blot GRK2 Antibody (3F8)
Immunocytochemistry/ Immunofluorescence GRK2 Antibody (3F8)
Immunohistochemistry GRK2 Antibody (3F8)
Immunohistochemistry-Paraffin GRK2 Antibody (3F8)
ELISA GRK2 Antibody (3F8)
Immunocytochemistry/ Immunofluorescence GRK2 Antibody (3F8)
Immunocytochemistry/ Immunofluorescence GRK2 Antibody (3F8)
Species: Hu, Mu, Rt, Pm, Pm
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
GRK2 Antibody (2089B) [Unconj ...
GRK2 Antibody (2089B) [Unconjugated]
MAB43391
HAF008). A specific band was detected for GRK2 at approximately 76 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot GRK2 Antibody (2089B) [Unconjugated]
Simple Western GRK2 Antibody (2089B) [Unconjugated]
HAF008). A specific band was detected for GRK2 at approximately 76 kDa (as indicated) in the parental HEK293T cell line, but is not detectable in knockout HEK293T cell line. GAPDH (Catalog # MAB5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Knockout Validated GRK2 Antibody (2089B) [Unconjugated]
Western Blot GRK2 Antibody (2089B) [Unconjugated]
Species: Hu, Mu, Rt
Applications: WB, Simple Western, KO
Host: Rabbit Monoclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 FAB43391U-100UG
Alexa Fluor 405 FAB43391V-100UG
Alexa Fluor 488 FAB43391G-100UG
Alexa Fluor 532 FAB43391X-100UG
Alexa Fluor 594 FAB43391T-100UG
Alexa Fluor 647 FAB43391R-100UG
Alexa Fluor 700 FAB43391N-100UG
Alexa Fluor 750 FAB43391S-100UG
Alexa Fluor Plus 405 FAB43391AFP405-100UG
Alexa Fluor Plus 488 FAB43391AFP488-100UG
Alexa Fluor Plus 555 FAB43391AFP555-100UG
Alexa Fluor Plus 594 FAB43391AFP594-100UG
Alexa Fluor Plus 647 FAB43391AFP647-100UG
Alexa Fluor Plus 680 FAB43391AFP680-100UG
Allophycocyanin FAB43391A
Biotin FAB43391B
CoraFluor 1 FAB43391CL1
DyLight 350 FAB43391D
DyLight 405 FAB43391E
DyLight 488 FAB43391K
DyLight 550 FAB43391L
DyLight 594 FAB43391M
DyLight 650 FAB43391W
DyLight 680 FAB43391Y
DyLight 755 FAB43391Z
FITC FAB43391F
HRP FAB43391H
Janelia Fluor 525 FAB43391JF525
Janelia Fluor 549 FAB43391I
Janelia Fluor 646 FAB43391J
Janelia Fluor 669 FAB43391JF669
PE FAB43391P
PerCP FAB43391C
mFluor Violet 450 SE FAB43391MFV450
mFluor Violet 500 SE FAB43391MFV500
mFluor Violet 610 SE FAB43391MFV610
Formulation Catalog # Availability Price  
Carrier Free MAB43391-100
Carrier Free MAB43391-SP
GRK2 Antibody [Unconjugated]
GRK2 Antibody [Unconjugated]
AF4339
HAF016). A specific band was detected for GRK2 at approximately 79 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot GRK2 Antibody [Unconjugated]
CTS013). Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS019) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of neurons. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry GRK2 Antibody [Unconjugated]
HAF016). A specific band was detected for GRK2 at approximately 76 kDa (as indicated) in the parental HEK293T cell line, but is not detectable in knockout HEK293T cell line. GAPDH (Catalog # AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Knockout Validated GRK2 Antibody [Unconjugated]
Species: Hu, Mu, Rt
Applications: WB, IHC, KO
Host: Sheep Polyclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 AF4339U-100UG
Alexa Fluor 405 AF4339V-100UG
Alexa Fluor 488 AF4339G-100UG
Alexa Fluor 532 AF4339X-100UG
Alexa Fluor 594 AF4339T-100UG
Alexa Fluor 647 AF4339R-100UG
Alexa Fluor 700 AF4339N-100UG
Alexa Fluor 750 AF4339S-100UG
Alexa Fluor Plus 405 AF4339AFP405-100UG
Alexa Fluor Plus 488 AF4339AFP488-100UG
Alexa Fluor Plus 555 AF4339AFP555-100UG
Alexa Fluor Plus 594 AF4339AFP594-100UG
Alexa Fluor Plus 647 AF4339AFP647-100UG
Alexa Fluor Plus 680 AF4339AFP680-100UG
Allophycocyanin AF4339A
Biotin AF4339B
CoraFluor 1 AF4339CL1
DyLight 350 AF4339D
DyLight 405 AF4339E
DyLight 488 AF4339K
DyLight 550 AF4339L
DyLight 594 AF4339M
DyLight 650 AF4339W
DyLight 680 AF4339Y
DyLight 755 AF4339Z
FITC AF4339F
HRP AF4339H
Janelia Fluor 525 AF4339JF525
Janelia Fluor 549 AF4339I
Janelia Fluor 646 AF4339J
Janelia Fluor 669 AF4339JF669
PE AF4339P
PerCP AF4339C
mFluor Violet 450 SE AF4339MFV450
mFluor Violet 500 SE AF4339MFV500
mFluor Violet 610 SE AF4339MFV610
Formulation Catalog # Availability Price  
Carrier Free AF4339-SP
Read More
Read More
Read More
See All GRK2 Products
We have 25 GRK2 Antibodies
ELISA Kits
Rat GRK2 ELISA Kit (Colorimet ...
Rat GRK2 ELISA Kit (Colorimetric)
NBP2-66688
ELISA Rat GRK2 ELISA Kit (Colorimetric)
ELISA Rat GRK2 ELISA Kit (Colorimetric)
Species: Rt
Applications: ELISA
Human GRK2 ELISA Kit (Colorim ...
Human GRK2 ELISA Kit (Colorimetric)
NBP3-53447
ELISA Human GRK2 ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
Human GRK2 - Ready-To-Use EL ...
Human GRK2 - Ready-To-Use ELISA K...
NBP3-53041
ELISA Human GRK2 - Ready-To-Use ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
Read More
Read More
Read More
See All GRK2 Products
We have 3 GRK2 ELISA Kits
Lysates
GRK2 Overexpression Lysate
GRK2 Overexpression Lysate
NBP2-10984
Western Blot GRK2 Overexpression Lysate
Species: Hu
Applications: WB
Read More
See All GRK2 Products
We have 1 GRK2 Lysate
Proteins
Recombinant Human GRK2 GST (N ...
Recombinant Human GRK2 GST (N-Term...
H00000156-P01
SDS-Page Recombinant Human GRK2 GST (N-Term) Protein
Species: Hu
Applications: WB, ELISA, Endotoxin, AP
GRK2 Recombinant Protein Anti ...
GRK2 Recombinant Protein Antigen
NBP2-57283PEP
Species: Hu
Applications: AC
Read More
Read More
See All GRK2 Products
We have 2 GRK2 Proteins

Description

Adrenergic Receptor beta Kinase 1 (ADRBK1), also known as GRK2, is a member of the G-protein receptor kinase family. A ubiquitous cytosolic enzyme, GRK-2 specifically phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed under high agonist concentrations. Defects in GRK2 coupling with G-protein receptors may lead to heart failure.

Bioinformatics

Entrez
110355
Mouse
156
Human
25238
Rat
Uniprot
AAH37963.1
Human
NP_001610
Human
P25098
Human
Product By Gene ID 156
Alternate Names
  • adrenergic, beta, receptor kinase 1
  • BARK
  • BARK1beta-ARK-1
  • BETA-ARK1
  • Beta-ARK-1
  • EC 2.7.11
  • EC 2.7.11.15
  • FLJ16718
  • G-protein coupled receptor kinase 2
  • GRK2beta-adrenergic receptor kinase 1

Research Areas for GRK2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cellular Markers
Mitochondrial Markers
Neuroscience
Phospho-Specific
Protein Kinase
Signal Transduction

Related GRK2 Blog Posts

Check out the latest blog posts on GRK2.
"Freeze!" - Arrestin Antibodies Used in New Serotonin Syndrome Study
The beta-arrestin family regulate receptor binding of G-proteins, a group of seven transmembrane receptor proteins which includes the adrenergic, dopamine and serotonin receptors. Recently, arrestin antibodies were used in a study into Serotonin Syndr...    Read more.
Read more GRK2 related blogs.