| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NB120-10454SS | |||
| Azide and BSA Free | NBP2-80612 | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NBP2-80099 | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NBP2-80100 | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NBP2-80099 | |||
![Western Blot: Caspase-11 Antibody (17D9) [NB120-10454] - Mouse liver extract was separated on a 4-15% gel and transfered to PVDF membrane. The membrane was probed with anti-caspase 11 antibody and detected with an anti-rat HRP secondary antibody. Both procaspase 11 and fully cleaved caspase 11 are detected.](http://images.novusbio.com/fullsize/Caspase-11-Antibody-17D9-Western-Blot-NB120-10454-img0003.jpg "Western Blot: Caspase-11 Antibody (17D9) [NB120-10454] - Mouse liver extract was separated on a 4-15% gel and transfered to PVDF membrane. The membrane was probed with anti-caspase 11 antibody and detected with an anti-rat HRP secondary antibody. Both procaspase 11 and fully cleaved caspase 11 are detected.")
![Immunohistochemistry-Paraffin: Caspase-11 Antibody (17D9) [NB120-10454] - IHC-P analysis of a formalin fixed paraffin embedded tissue section of mouse lung using Caspase 11 antibody (clone 17D9) at 1:100 diluton. The antibody generated cytoplasmic signal with more intense staining in the bronchiolar epithelium while the staining signal in alveolar cells was relatively low.](http://images.novusbio.com/fullsize/Caspase-11-Antibody-17D9-Immunohistochemistry-Paraffin-NB120-10454-img0006.jpg)
![<b>Biological Strategies Validation. </b>Western Blot: Caspase-11 Antibody (17D9) [NB120-10454] - Analysis of Caspase-11 in THP-1 cell lysates that were untreated (left lane) or treated (right lane) with 100 ng/ml LPS. Image from verified customer review.](http://images.novusbio.com/fullsize/Caspase-11-Antibody-17D9-Western-Blot-NB120-10454-img0007.jpg)
![Immunocytochemistry/Immunofluorescence: Caspase-11 Antibody (17D9) [NB120-10454] - Caspase 11 antibody was tested in NIH-3T3 cells at a 1:100 dilution using a Dylight 488 conjugated secondary antibody (Green). Actin (Red) and DNA (Blue) were counterstained using Phalloidin 568 and DAPI.](http://images.novusbio.com/fullsize/Caspase-11-Antibody-17D9-Immunocytochemistry-Immunofluorescence-NB120-10454-img0004.jpg)
![<b>Biological Strategies Validation. </b>Western Blot: Caspase-11 Antibody (17D9) [NB120-10454] - Caspase 11 Antibody (17D9) [NB120-10454] - analysis of Caspase 11 in LPS stimulated bone marrow derived macrophages using anti-Caspase 11 antibody. Image from verified customer review.](http://images.novusbio.com/fullsize/Caspase-11-Antibody-17D9-Western-Blot-NB120-10454-img0005.jpg)
![<b>Genetic Strategies Validation. </b>Western Blot: Caspase-11 Antibody (17D9) [NB120-10454] - Casp11fl/fl and Casp11EC-/- mice (n = 3) were challenged with LPS (40 mg/kg i.p.) for 6 hours. Endothelial Cells were isolated from lungs, and western blot analysis was performed for pro-IL-1Beta, mature IL-1Beta, and caspase-1 cleavage. This image is from PMID: 28990935.](http://images.novusbio.com/fullsize/Caspase-11-Antibody-17D9-Knockout-Validated-NB120-10454-img0008.jpg)
![<b>Genetic Strategies Validation. </b>Western Blot: Caspase-11 Antibody (17D9) [NB120-10454] - CNF1-triggered immunity requires inflammatory caspases.(A and B) IL-1beta production and maturation/secretion after treatment with CNF1, LPS or CNF1 (1 ug/ml) + LPS (100 ng/ml) for 10 h. Actin and BSA were used as loading controls. Image collected and cropped by CiteAb from the following publication (//dx.plos.org/10.1371/journal.ppat.1004732), licensed under a CC-BY license.](http://images.novusbio.com/fullsize/Caspase-11-Antibody-17D9-Knockout-Validated-NB120-10454-img0009.jpg)
![<b>Genetic Strategies Validation. </b>Western Blot: Caspase-11 Antibody (17D9) [NB120-10454] - CNF1-triggered IL-1beta maturation requires activated Rac, ASC and caspase-1. Western blot analysis of the production and maturation/secretion of IL-1beta by primary macrophages following treatment with CNF1, LPS or CNF1+LPS for 10 h. Actin and BSA were used as loading controls. Image collected and cropped by CiteAb from the following publication (//dx.plos.org/10.1371/journal.ppat.1004732), licensed under a CC-BY license.](http://images.novusbio.com/fullsize/Caspase-11-Antibody-17D9-Knockout-Validated-NB120-10454-img0010.jpg)
![<b>Genetic Strategies Validation. </b>Western Blot: Caspase-11 Antibody (17D9) [NB120-10454] - Caspase-11 is expressed in Casp1Null bone marrow-derived macrophages. Immunoblot analysis of caspase-1, caspase-11 and GAPDH (loading control) in unprimed WT at various times (above lane) after stimulation with IFN-beta (250U/ml), IFN-gamma (100 ng/ml) or LPS (100 ng/ml). Data are representative of two independent experiments. Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/srep45126), licensed under a CC-BY license.](http://images.novusbio.com/fullsize/Caspase-11-Antibody-17D9-Knockout-Validated-NB120-10454-img0011.jpg)
![Western Blot: Caspase-11 Antibody (17D9) - BSA Free [NB120-10454] - Histone induce BMECs pyroptosis is dependent on activations of caspase 1, caspase 3 & NLRP3. BMECs were incubated with stimulated histone for 16 h, & the activities of these proteins were determined by western blotting. Date are presented as mean ± SEM (n = 5). P-values of < 0.05 were considered significant (**P < 0.01, ***P < 0.001, & “ns” means not significant). Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/31156617), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb120-10454_rat-monoclonal-caspase-11-antibody-17d9-310202415175277.jpg)
![Western Blot: Caspase-11 Antibody (17D9) - BSA Free [NB120-10454] - Caspase-11 is expressed in Casp1Null bone marrow-derived macrophages.Immunoblot analysis of caspase-1, caspase-11 & GAPDH (loading control) in unprimed WT or mutant BMDMs at various times (above lane) after stimulation with IFN-beta (250U/ml), IFN-gamma (100 ng/ml) or LPS (100 ng/ml). Data are representative of two independent experiments. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/28345580), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb120-10454_rat-monoclonal-caspase-11-antibody-17d9-31020241529336.jpg)
![Immunohistochemistry: Caspase-11 Antibody (17D9) - BSA Free [NB120-10454] - Immunocytochemistry analysis of histone induced activations of caspase 1, caspase 3, & NLRP3 (400×). BMECs were cultured briefly on cover glasses (pre-treated with poly-L –lysine, 0.1 mg/mL, Sigma-Aldrich) & incubated with histone (50 & 100 μg/mL) for 16 h. The samples were visualized with DAB, counterstained with hematoxylin & observed by inverted microscope. Three independent experiments were carried out by light microscope analyses. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/31156617), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb120-10454_rat-monoclonal-caspase-11-antibody-17d9-310202415291954.jpg)
![Western Blot: Caspase-11 Antibody (17D9) - BSA Free [NB120-10454] - Differential roles of caspase-1 & caspase-11 in response to infection with Aspergillus fumigatus.(A) Immunoblot analysis of pro-caspase-1 (Pro-Casp-1) & the caspase-1 subunit p20 (Casp-1 p20) & GAPDH (loading control) in unprimed WT or mutant bone marrow-derived dendritic cells left untreated (medium alone [Med]) or assessed 20 h after infection with A. fumigatus (MOI, 10). (B) Release of IL-1 beta & IL-18 after treatment as in (A). (C) Survival of 8-week-old WT & mutant mice infected with 5 × 105 A. fumigatus conidia after immunosuppression with cyclophosphamide & cortisone acetate. *P < 0.05, ****P < 0.0001 (log-rank test). Data are representative of two (C) or three independent experiments (A & B; mean & s.e.m. are representative of values from three independent experiments in B). Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/28345580), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb120-10454_rat-monoclonal-caspase-11-antibody-17d9-3102024162183.jpg)
![Western Blot: Caspase-11 Antibody (17D9) - BSA Free [NB120-10454] - GBP2 & IRGB10 regulates caspase-11 mediated non-canonical NLRP3 activation & pyroptosis.a Microscopic analysis of cell death in unprimed WT, Gbp2−/−, Gbp5−/−, Gbpchr3-KO,Irgb10−/−, Irgb10−/−Gbpchr3-KO, Caspase11−/− & Nlrp3−/− BMDMs infected with popB (MOI 10) for 16 h. (Scale, 15 μm). Arrow heads indicate pyroptotic cells. b–e Immunoblot analysis of caspase-1, IL-1 beta , IL-18, & IL-6 release in WT, Gbp2−/−, Gbp5−/−, Gbpchr3-KO, Irgb10−/−, Irgb10−/−Gbpchr3-KO, Caspase11−/− & Nlrp3−/− BMDMs infected with popB (MOI10). f Bacterial CFU in unprimed WT, Gbp2−/−, Gbp5−/−, Gbpchr3-KO, Irgb10−/−, Irgb10−/−Gbpchr3-KO, Caspase11−/− & Nlrp3−/− BMDMs infected with popB (MOI10), 4 h & 16 h. Data are representative of three independent experiments. ns-not significant, *p < 0.05, **p < 0.01, ***p < 0.001,****p < 0.0001 (two-tailed T test) Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30062052), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb120-10454_rat-monoclonal-caspase-11-antibody-17d9-310202416212381.jpg)
![Flow Cytometry: Caspase-11 Antibody (17D9) - BSA Free [NB120-10454] - The expression of circHIPK3 in serum samples of patients with AP & in caerulein-stimulated pancreatic acinar cells. (A) QPCR was performed to detect circHIPK3 expression in serum samples of patients with AP & healthy subjects. MAP, mild acute pancreatitis; SAP, severe Acute Pancreatitis. (B) CCK8 assay was performed to measure the cell viability in AR42J cells after caerulein treatment. (C) Levels of inflammatory cytokines IL-1 beta , IL-6, IL-8, & TNF-alpha were measured by ELISA kits in culture medium after caerulein treatment. (D) Amylase activity was measured by ELISA kit in AR42J cells after caerulein treatment. (E) The pyroptosis-related proteins caspase 1 & caspase 11 were analyzed by immunoblot in AR42J cells after caerulein treatment. (F) PI staining was performed in AR42J cells after caerulein treatment, & the PI-positive cells were counted. (G) Flow-cytometric analysis of caspase-1/11+PI+ cells in AR42J cells after caerulein treatment. Data are presented as a representative plot (upper) & quantified percentages (lower). (H) circHIPK3 expression was determined by qPCR in AR42J cells after caerulein treatment. *p < 0.05. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/32318575), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb120-10454_rat-monoclonal-caspase-11-antibody-17d9-31020241621839.jpg)
![Western Blot: Caspase-11 Antibody (8A5) - BSA Free [NBP2-80099] - Using Caspase-11 (mouse), mAb (8A5) (Prod. No. NBP2-80099)](http://images.novusbio.com/fullsize/Caspase-11-Antibody-8A5-BSA-Free-Western-Blot-NBP2-80099-img0001.jpg "Western Blot: Caspase-11 Antibody (8A5) - BSA Free [NBP2-80099] - Using Caspase-11 (mouse), mAb (8A5) (Prod. No. NBP2-80099)")
![Caspase-11 Antibody (8A5) - BSA Free [NBP2-80099] - Of caspase-11 using anti-caspase-11 mAbs (4E11 and 8A5) (Prod. No. NBP2-80099).](http://images.novusbio.com/fullsize/Caspase-11-Antibody-8A5-BSA-Free-NBP2-80099-img0002.jpg)
![Caspase-11 Antibody (8A5) - BSA Free [NBP2-80099] - Data of overexpressed FLAG-tagged caspase-11 in 293T cells using Caspase-11 mAbs (4E11 and 8A5) (Prod. No. NBP2-80099)](http://images.novusbio.com/fullsize/Caspase-11-Antibody-8A5-BSA-Free-NBP2-80099-img0003.jpg)
![Western Blot: Caspase-11 Antibody (4E11) - BSA Free [NBP2-80100] - Using Caspase-11 (mouse), mAb (4E11) (Prod. No.NBP2-80100)](http://images.novusbio.com/fullsize/Caspase-11-Antibody-4E11-BSA-Free-Western-Blot-NBP2-80100-img0001.jpg "Western Blot: Caspase-11 Antibody (4E11) - BSA Free [NBP2-80100] - Using Caspase-11 (mouse), mAb (4E11) (Prod. No.NBP2-80100)")
![Flow Cytometry: Caspase-11 Antibody (4E11) - BSA Free [NBP2-80100] - Data of overexpressed FLAG-tagged caspase-11 in 293T cells using Caspase-11 mAbs (4E11 and 8A5) (Prod. No. NBP2-80100)](http://images.novusbio.com/fullsize/Caspase-11-Antibody-4E11-BSA-Free-Flow-Cytometry-NBP2-80100-img0003.jpg)
![Immunoprecipitation: Caspase-11 Antibody (4E11) - BSA Free [NBP2-80100] - Of caspase-11 using anti-caspase-11 mAbs (4E11 and 8A5) (Prod. No. NBP2-80100).](http://images.novusbio.com/fullsize/Caspase-11-Antibody-4E11-BSA-Free-Immunoprecipitation-NBP2-80100-img0002.jpg)
![ELISA: Mouse Caspase-11 ELISA Kit (Chemiluminescence) [NBP2-75019] - Samples were spiked with high concentrations of Mouse Caspase-11 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.](http://images.novusbio.com/fullsize/nbp2-75019_mouse-caspase-11-elisa-kit-chemiluminescence-132202416243467.jpg "ELISA: Mouse Caspase-11 ELISA Kit (Chemiluminescence) [NBP2-75019] - Samples were spiked with high concentrations of Mouse Caspase-11 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.")
![ELISA: Mouse Caspase-11 ELISA Kit (Chemiluminescence) [NBP2-75019] - Standard Curve Reference](http://images.novusbio.com/fullsize/nbp2-75019_mouse-caspase-11-elisa-kit-chemiluminescence-4320249192850.jpg)
![Caspase-11 Antibody (8A5) [Alexa Fluor® 350] [NBP2-80099AF350] - Vial of Alexa Fluor 350 conjugated antibody. Alexa Fluor 350 is optimally excited at 346 nm by the UV laser (350 or 355 nm) and has an emission maximum of 442 nm.](http://images.novusbio.com/fullsize/nbp2-80099af350_rat-caspase-11-mab-8a5-alexa-fluor-350-29820239282331.jpg "Caspase-11 Antibody (8A5) [Alexa Fluor® 350] [NBP2-80099AF350] - Vial of Alexa Fluor 350 conjugated antibody. Alexa Fluor 350 is optimally excited at 346 nm by the UV laser (350 or 355 nm) and has an emission maximum of 442 nm.")