Fibrinogen gamma chain Products

Description

The protein encoded by the Fibrinogen gamma chain gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Bioinformatics

Entrez	2266 Human
Uniprot	AAH07044 Human NM_000509 Human Q53Y18 Human
Product By Gene ID	2266
Alternate Names	fibrinogen gamma chain fibrinogen, gamma polypeptide

Research Areas for Fibrinogen gamma chain

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Angiogenesis
Cancer

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