Species: Hu, Mu, Rt
Applications: WB, IHC, IP, ICC/IF
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB, KO
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).
Bioinformatics
| Entrez |
Human
Rat
|
| Uniprot |
Bovine
|
| Product By Gene ID |
1644 |
| Alternate Names |
- AADC
- AADCaromatic-L-amino-acid decarboxylase
- DDC
- dopa decarboxylase (aromatic L-amino acid decarboxylase)
- Dopa Decarboxylase
- EC 4.1.1
- EC 4.1.1.28
|
Research Areas for Dopa Decarboxylase/DDC
Find related products by research area and learn more about each of the different research areas below.
Neuroscience
![Western Blot Dopa Decarboxylase/DDC Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Dopa_Decarboxylase_AF3564_Western_Blot_17092.jpg)
![Immunocytochemistry Dopa Decarboxylase/DDC Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Dopa_Decarboxylase_AF3564_Immunocytochemistry__Immunofluorescence_19968.jpg)
![Immunohistochemistry Dopa Decarboxylase/DDC Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Dopa_Decarboxylase_AF3564_Immunohistochemistry_19241.jpg)
![Immunohistochemistry Dopa Decarboxylase/DDC Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Dopa_Decarboxylase_AF3564_Immunohistochemistry_19242.jpg)
![Immunocytochemistry/ Immunofluorescence Dopa Decarboxylase/DDC Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af3564_human-mouse-rat-dopa-decarboxylase-ddc-affinity-purified-pab-4120241240214.jpg)
![Western Blot Dopa Decarboxylase/DDC Antibody (413911) [Unconjugated]](http://images.novusbio.com/fullsize2/Dopa_Decarboxylase_MAB3564_Western_Blot_6115.jpg)
![Knockout Validated Dopa Decarboxylase/DDC Antibody (413911) [Unconjugated]](http://images.novusbio.com/fullsize2/Dopa_Decarboxylase_MAB3564_Knockout_Validated_23201.jpg)
