Zyxin Products

Description

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

Bioinformatics

Entrez	114636 Rat 22793 Mouse 7791 Human
Uniprot	AAH08743 Human NP_001010972 Human NP_001010972.1 Human NP_003452.1 Human Q15942 Human
Product By Gene ID	7791
Alternate Names	CTCL tumor antigen se14-3 CTCL-associated antigen se14-3 cutaneous T-cell lymphoma associated antigen se14-3 Cutaneous T-cell lymphoma-associated antigen se14-3 KIAA1125 MGC31836 predicted protein of HQ2893 PRKCBP1 PRO2893 protein kinase C-binding protein 1 Rack7 RACK7protein kinase C binding protein 1 zinc finger MYND domain containing protein 8 Zinc finger MYND domain-containing protein 8 zinc finger, MYND-type containing 8

Research Areas for Zyxin

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction