ZIC1 Products

Antibodies
ZIC1 Antibody
ZIC1 Antibody
NB600-488
Species: Hu, Mu, Rat
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
ZIC1 Antibody [Unconjugated]
ZIC1 Antibody [Unconjugated]
AF4978
Species: Hu, Mu
Applications: WB, IHC, ICC
Host: Goat Polyclonal
ZIC1 Antibody
ZIC1 Antibody
NBP1-86833
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ZIC1 Overexpression Lysate (N ...
ZIC1 Overexpression Lysate (Native)
NBP2-08012
Applications: WB
Proteins
ZIC1 Partial Recombinant Prot ...
ZIC1 Partial Recombinant Protein
H00007545-Q01
Species: Hu
Applications: WB, ELISA, PA
ZIC1 Recombinant Protein Anti ...
ZIC1 Recombinant Protein Antigen
NBP1-86833PEP
Species: Hu
Applications: AC
RNAi
ZIC1 RNAi
ZIC1 RNAi
H00007545-R01
Species: Hu

Description

The Zic-1 gene, which encodes a zinc finger protein, is expressed in the developing or matured central nervous system in a highly restricted manner. The Zic gene is expressed in granule cells that make synaptic contact with Purkinje cells. Clearly Zic-1 is a gene critical to cerebellar pattern formation. The expression of Zic genes is first detected at gastrulation and at neurulation, becomes restricted to the dorsal neural ectoderm and the dorsal paraxial mesoderm. Zic-2 and Zic-3 are highly similar genes, especially in their product's zinc finger motif and by comparison of their genomic organization in that they share common exon-intron boundaries and belong to the same gene family. By comparison in function, Zic-2 is essential for the formation of the brain and Zic-3 is important for right and left axis formation. The Zic-1 gene has been mapped to chromosome 9 in mouse. The 5' flanking region of the Zic-1 gene contains a region-specific enhancer determined to be essential in in vivo and in vitro deletion analysis. The temporal profile of mRNA expression differs for each of the Zic gene products. The Drosophila odd-paired gene is highly homologous to the Zic gene family.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 7545
Alternate Names
  • Zinc finger protein 201
  • ZNF201zinc finger protein ZIC 1
  • ZICZic family member 1 (odd-paired Drosophila homolog)
  • Zinc finger protein of the cerebellum 1
  • Zic family member 1 (odd-paired homolog, Drosophila)

Research Areas for ZIC1

Find related products by research area and learn more about each of the different research areas below.

Growth and Development
Neuronal Cell Markers
Neuroscience
Signal Transduction

PTMs for ZIC1

Learn more about PTMs related to ZIC1.

Methylation
Demethylation
Phosphorylation

Bioinformatics Tool for ZIC1

Discover related pathways, diseases and genes to ZIC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.